Pivotal study of MRI-guided transurethral ultrasound ablation (TULSA) of localized prostate cancer: 5-year follow up

S Eggener, G Zagaja, A Oto, C Pavlovich… - … Oncology: Seminars and …, 2024 - Elsevier
Introduction Magnetic resonance imaging-guided transurethral ultrasound ablation (TULSA)
of the prostate uses ultrasound to thermally coagulate tissue under real-time MRI guidance.
Real-time feedback from closed-loop MRI thermometry automatically controls treatment
parameters to match tissue response in the prescribed ablation volume. The pivotal study of
TULSA (“TACT”, NCT02766543), which included a low-to intermediate-risk prostate cancer
(PCa) population, has reached the end of the 5-year follow-up duration. Here we report the …
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