[HTML][HTML] Placebo-induced pain reduction is associated with negative coupling between brain networks at rest

IC Wagner, M Rütgen, A Hummer, C Windischberger… - Neuroimage, 2020 - Elsevier
… and underwent resting-state fMRI after pain processing. Results … on pain engages brain
regions that signal pain anticipation, … To further investigate placebo-induced changes in intrinsic …

[HTML][HTML] Placebo treatment affects brain systems related to affective and cognitive processes, but not nociceptive pain

R Botvinik-Nezer, B Petre, M Ceko… - Nature …, 2024 - nature.com
… mechanical pain trials, we found significant placebo-induced … analgesia and neural
placebo-induced changes, as was … (as in most previous placebo fMRI studies) are unreliable, and …

[HTML][HTML] Meta-analysis of neural systems underlying placebo analgesia from individual participant fMRI data

M Zunhammer, T Spisák, TD Wager, U Bingel - Nature communications, 2021 - nature.com
… 11 , a mega-analysis of placebo-induced brain activity can be … negatively correlated with
placebo-induced changes in brain … decreases in areas strongly activated in pain. The strongest …

Neurocognition and placebo analgesia: Linking in functional magnetic resonance imaging

S Palermo - The Neurobiology, Physiology, and Psychology of Pain, 2022 - Elsevier
pain could cause bias in the evaluation of the pain experienced in the fMRI acquisition phase
due to the “painful … Several studies have proposed that the anticipation of pain triggers a …

The placebo phenomenon and the underlying mechanisms

P Theodosis-Nobelos, A Filotheidou, C Triantis - Hormones, 2021 - Springer
… experiencing decreased levels of pain. This model of placebo-induced analgesia can be …
perceived as a cognitive engagement involving the anticipation of an event that has proved to …

The neurobiological underpinnings of placebo and nocebo effects

F Benedetti, A Piedimonte - Seminars in Arthritis and Rheumatism, 2019 - Elsevier
… conditions and therapeutic interventions, pain is the field where … , ranging from endogenous
pain modulation to anxiety … a related mechanism in placebo-induced and opioid-induced …

[HTML][HTML] A social affective neuroscience lens on placebo analgesia

LY Atlas - Trends in Cognitive Sciences, 2021 - cell.com
fMRI studies that compare placebo administration with a control treatment (ie, no expected
pain relief) indicate that pain-… Images of placebo-induced reductions (upper middle) were …

Brainstem mechanisms of pain modulation: a within-subjects 7T fMRI study of placebo analgesic and nocebo hyperalgesic responses

LS Crawford, EP Mills, T Hanson… - Journal of …, 2021 - Soc Neuroscience
… This study used ultra-high-field 7 tesla functional MRI (fMRI) to accurately resolve … modulate
their pain relative to a third Vaseline (control) cream. In a subsequent test phase, fMRI image …

[HTML][HTML] Neural effects of placebo analgesia in fibromyalgia patients and healthy individuals

E Frangos, M Ceko, B Wang, EA Richards, JL Gracely… - Pain, 2021 - journals.lww.com
… activations during placebo-induced expectation of pain relief … The black arrows indicate
the anticipation period and heat … pain and discomfort with experimental pain ratings and fMRI

[HTML][HTML] The neural processes of acquiring placebo effects through observation

LA Schenk, L Colloca - Neuroimage, 2020 - Elsevier
… imaging (fMRI) … experienced lower pain intensity and unpleasantness during the placebo
condition, confirming that observational learning can lead to placebo-induced reductions of pain