Acquisition of Antibodies Against Endothelial Protein C Receptor–Binding Domains of Plasmodium falciparum Erythrocyte Membrane Protein 1 in Children with …

JS Rambhatla, L Turner, L Manning… - The Journal of …, 2019 - academic.oup.com
… malaria is associated with widespread organ sequestration [13, … Domain cassettes (DCs)
are conserved sets of PfEMP1 … clinical information, 1 experiment failed, and 8 had P. vivax …

Acquisition of IgG to ICAM-1-binding DBLβ domains in the Plasmodium falciparum erythrocyte membrane protein 1 antigen family varies between groups A, B, and C

RW Olsen, G Ecklu-Mensah, A Bengtsson… - Infection and …, 2019 - Am Soc Microbiol
… A ICAM-1-binding DBLβ domains associated with cerebral … group B and C PfEMP1 proteins,
with domain cassettes (DC) … group A prior to group B and C domains (13). In addition, it has …

Antigenic cartography of immune responses to Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1)

J Tuju, MJ Mackinnon, AI Abdi, H Karanja… - PLoS …, 2019 - journals.plos.org
… Some var genetic groups have been consistently associated with severe disease, denoted …
[13], domain cassettes 8 and 13 [14], the REY motif at the PoLV2 position of the DBLα domain

… of Protective Antibodies against Severe Malaria in Papua, Indonesia, Using Locally Expressed Domains of Plasmodium falciparum Erythrocyte Membrane Protein 1

JS Rambhatla, GQ Tonkin-Hill, E Takashima… - Infection and …, 2022 - Am Soc Microbiol
… been most consistently associated with severe malaria (8… -6 domains often bind to CD36 (13,
14), and DBLβ domains often … domain cassette (DC) are indicated (35). Only a proportion of …

Antibody Levels to Plasmodium falciparum Erythrocyte Membrane Protein 1-DBLγ11 and DBLδ-1 Predict Reduction in Parasite Density

BN Araj, B Swihart, R Morrison, P Gonzales Hurtado… - Msystems, 2021 - Am Soc Microbiol
… with DC8 and DC13 domain cassettes that were previously … positive response to an
antigen ranged from 13% to 74%. The … and DBLδ1 domains were associated with decreased …

Role of Plasmodium falciparum protein GEXP07 in Maurer's cleft morphology, knob architecture, and P. falciparum EMP1 trafficking

…, D Andrew, S Batinovic, AJY Low, HJ Cho, P McMillan… - MBio, 2020 - Am Soc Microbiol
falciparum erythrocyte membrane protein 1 (PfEMP1) to the … We identified 13 previously
uncharacterized or poorly … We were unable to detect a RBC membrane-associated population of …

Dissecting the gene expression, localization, membrane topology, and function of the Plasmodium falciparum STEVOR protein family

JS Wichers, JAM Scholz, J Strauss, S Witt, A Lill… - MBio, 2019 - Am Soc Microbiol
… , indicating that 9 variants from chromosomes 1, 8, and 13 were not expressed. Subsequent
… rhoptry-associated STEVOR PF3D7_0631900 in erythrocyte invasion, we investigated its …

Structural insights into diverse modes of ICAM-1 binding by Plasmodium falciparum-infected erythrocytes

F Lennartz, C Smith, AG Craig… - Proceedings of the …, 2019 - National Acad Sciences
… We find that this can happen in 2 different but related ways, … Plasmodium falciparum
erythrocyte membrane proteins 1 (… ), and intercellular adhesion molecule 1 (ICAM-1) (13–15). …

Updated List of Transport Proteins in Plasmodium falciparum

J Wunderlich - Frontiers in Cellular and Infection Microbiology, 2022 - frontiersin.org
… However, membrane proteins are less amenable to proteomic tools compared to soluble
parasite proteins, … Protein complex components residing in or associated with the respective …

A revised mechanism for how Plasmodium falciparum recruits and exports proteins into its erythrocytic host cell

M Gabriela, KM Matthews, C Boshoven… - PLoS …, 2022 - journals.plos.org
associate with other PV-resident proteins to retrieve cargo proteins [47], extract transmembrane
proteins … of the blasticidin deaminase drug resistance cassette. The plasmid pEF-Hyp1-…