Reactive oxygen species in macrophages: sources and targets

M Canton, R Sánchez-Rodríguez, I Spera… - Frontiers in …, 2021 - frontiersin.org
Reactive oxygen species (ROS) have been known for many years as fundamental for
macrophages to kill invasive microorganisms through the oxidative burst mediated by NADPH …

Reactive oxygen species (ROS) in macrophage activation and function in diabetes

E Rendra, V Riabov, DM Mossel, T Sevastyanova… - Immunobiology, 2019 - Elsevier
… , during respiratory burst in … cell signaling Although high levels of ROS are deleterious,
intermediate levels of ROS serve as an important short-lived second messenger in cell signaling

LPS tolerance inhibits cellular respiration and induces global changes in the macrophage secretome

J Gillen, T Ondee, D Gurusamy, J Issara-Amphorn… - Biomolecules, 2021 - mdpi.com
… Regulation of cellular signaling leads to changes in multiple … related to metabolism or reactive
oxygen species, we found distinct … and Respiratory Burst of Myeloid Cells in LR cells (A), …

HPCA1 is required for systemic reactive oxygen species and calcium cell-to-cell signaling and plant acclimation to stress

Y Fichman, SI Zandalinas, S Peck, S Luan… - … Plant Cell, 2022 - academic.oup.com
… directly subjected to stress (termed “local tissue”), and a state of activated ROS production,
driven by the function of respiratory burst oxidase homologs (RBOHs), the plant equivalents …

Reactive oxygen species: Role in carcinogenesis, cancer cell signaling and tumor progression

FL Sarmiento-Salinas, A Perez-Gonzalez… - Life Sciences, 2021 - Elsevier
… The activation of phagocytes, known as the “respiratory burst” is one of the best- characterized
processes of ROS generation catalyzed by the different isoforms of NOX (NOX1–5) and …

Functions of ROS in macrophages and antimicrobial immunity

M Herb, M Schramm - Antioxidants, 2021 - mdpi.com
… The term reactive oxygen species (ROS) describes a group … molecule, is more suitable as
a cellular signaling factor than O 2 ●− [29,… bacteria by the oxidative burst generated by Nox2. …

[HTML][HTML] Instrumental role for reactive oxygen species in the inflammatory response

D Fokam, D Hoskin - Frontiers in Bioscience-Landmark, 2020 - imrpress.com
… processes such as cell signaling, senescence, … cells, macrophages initiate a respiratory
burst, ie, the quick increase in intracellular ROS that gradually degrades damaged cells

Hydrogen peroxide mediates pro-inflammatory cell-to-cell signaling: a new therapeutic target for inflammation?

D Gunawardena, R Raju, G Münch - Neural regeneration …, 2019 - journals.lww.com
… The first reactive oxygen species in the chain, superoxide, is … , a phenomenon known as
respiratory burst” (de Rooij et al., … the respiratory burst is a mechanism by which macrophages

Leishmania donovani exploits macrophage heme oxygenase-1 to neutralize oxidative burst and TLR signaling–dependent host defense

S Saha, M Basu, S Guin, P Gupta… - The Journal of …, 2019 - journals.aai.org
… These results suggest that HO-1 on one hand inhibits reactive oxygen species generation
Cells were harvested and lysed using ice-cold lysis buffer (Cell Signaling Technology) …

Escaping the Phagocytic Oxidative Burst: The Role of SODB in the Survival of Pseudomonas aeruginosa Within Macrophages

L Cavinato, E Genise, FR Luly… - Frontiers in …, 2020 - frontiersin.org
Reactive oxygen species (ROS) are small oxygen-derived molecules that are used to control
infections by phagocytic cells… The primary antibodies used were: LC3 (Cell Signaling, Italy; #…