Safety, comfort, and responsible use of natural resources are motivating the work regarding road vehicles in the automotive research group at the DLR (German Aerospace Center) Institute of System Dynamics and Control. The present article presents an overview of the research activities of this group, including recent results on energy management, vehicle dynamics, and intelligence. Most of this research has been experimentally validated in the ROboMObil, a modular robotic electric vehicle with a highly integrated mechatronic chassis, developed by DLR. These activities are in particular taking advantage of the opportunities offered by digitalization, automation, and electrification in order to decrease the conflict between mobility demands and its harmful collateral effects.