Exosomes: diagnostic biomarkers and therapeutic delivery vehicles for cancer

L Jiang, Y Gu, Y Du, J Liu - Molecular pharmaceutics, 2019 - ACS Publications
… proteins, RNA, lipids, and cellular metabolites, exosomes can act … , exosomal nucleic acids
have a good clinical applicationtoward high activity, low toxicity, and more refined targeting. …

Molecular functions and therapeutic applications of exosomal noncoding RNAs in cancer

QW Liu, Y He, WW Xu - Experimental & molecular medicine, 2022 - nature.com
… , and small nucleolar RNAs, on tumor growth, metastasis, angiogenesis, and … the
current clinical implications concerning exosomal noncoding RNAs in cancer treatment. …

Exosomal RNAs: novel potential biomarkers for diseases—a review

J Wang, BL Yue, YZ Huang, XY Lan, WJ Liu… - International Journal of …, 2022 - mdpi.com
… isolation and purity, which would greatly benefit the research on the clinical applications
of exosomes as disease biomarkers. Despite the insights highlighted in this review, a more …

Exosomes: Their role in pathogenesis, diagnosis and treatment of diseases

H Aheget, L Mazini, F Martin, B Belqat, JA Marchal… - Cancers, 2020 - mdpi.com
… as to their potential therapeutic application as liquid biopsy … Exosomal RNA content is a
subset of cellular RNA and, in … , at least in part, to directing ncRNA sorting towards EVs, given the …

The significance of exosomal RNAs in the development, diagnosis, and treatment of gastric cancer

G Zhao, A Zhou, X Li, S Zhu, Y Wang, S Zhang, P Li - Genes, 2021 - mdpi.com
… of exosome and promote the potentially diagnostic and therapeutic application of exosomes
in … aid in the acquisition and spread of drug resistance property and limit drug activity toward

Tumor-derived extracellular vesicles: reliable tools for Cancer diagnosis and clinical applications

R Rahbarghazi, N Jabbari, NA Sani, R Asghari… - Cell Communication and …, 2019 - Springer
Exosomal miRNAs hold great promise for clinical application in early diagnosis and treatment
… pri-RNAs into pre-miRNAs form, which is transferred toward cytoplasm employing exportin-…

Application of exosomes as liquid biopsy in clinical diagnosis

B Zhou, K Xu, X Zheng, T Chen, J Wang… - … and targeted therapy, 2020 - nature.com
… of exosomes in clinical applications, a commercial chain of … Diverse forms of exosomal RNAs
also promisingly take part … showed a substantial trend toward an inflammatory environment …

Exosomes and their importance in metastasis, diagnosis, and therapy of colorectal cancer

H Cheshomi, MM Matin - Journal of cellular biochemistry, 2019 - Wiley Online Library
toward the development of cancer diagnosis and therapy, … revealed that exosomal Hox
antisense intergenic RNA, as one … some challenges in the clinical application of exosomes, some …

Exosomes as a next-generation diagnostic and therapeutic tool in prostate cancer

S Gaglani, E Gonzalez-Kozlova, DJ Lundon… - International Journal of …, 2021 - mdpi.com
… of cancer progression towards defining cancer type and … , even with a very small amount of
exosomal RNA [23]. One study … the clinical use of exosomes in diagnostics and therapeutics is …

RNA-based diagnostic and therapeutic strategies for cardiovascular disease

D Lu, T Thum - Nature Reviews Cardiology, 2019 - nature.com
… have natural tropism towards cardiomyocytes (both in vivo … downfalls that limit their use in
clinical applications, such as … Although exosomes contain proportionally fewer small RNAs