Regulatory T Cells in Mycobacterium tuberculosis Infection

P Cardona, PJ Cardona - Frontiers in immunology, 2019 - frontiersin.org
… Th17 cells are characterized mainly by the production of IL-17, which promotes the synthesis
of other pro-inflammatory cytokines, and chemokines (30). The transcription factor required …

… -related-orphan receptor gamma activity blocks the T helper 17/interleukin-17 pathway leading to attenuated pro-inflammatory human keratinocyte and skin responses

F Ecoeur, J Weiss, K Kaupmann, S Hintermann… - Frontiers in …, 2019 - frontiersin.org
IL-17-regulated gene expression in keratinocyte cell cultures. … Total, naive and memory CD4
+ T cells were isolated from … and inhibitory function of regulatory T-cells (Tregs) (49). PBMCs …

[HTML][HTML] Macrophage migration inhibitory factor regulates innate γδ T-cell responses via IL-17 expression

HK Kim, AB Garcia, E Siu, P Tilstam, R Das… - The FASEB …, 2019 - ncbi.nlm.nih.gov
T cells, when compared with wild type, were observed to produce >10-fold higher levels of
the proinflammatory cytokine IL-17 … sclerosis by pharmacologic MIF antagonism (55) suggests …

Exaggerated IL-17A activity in human in vivo recall responses discriminates active tuberculosis from latent infection and cured disease

…, A Folino, A Akarca, C Venturini, T Baker… - Science translational …, 2021 - science.org
T cell epitopes strongly suggests that T cell responses promote immunopathology (49) and
that their negative regulation is … able to detect increased IL-17 protein or T H 17 cells from the …

[HTML][HTML] Cutaneous tuberculosis: epidemiological, clinical, diagnostic and therapeutic update

AC Brito, CMM Oliveira, DAA Unger… - Anais Brasileiros de …, 2022 - SciELO Brasil
Regulatory T cells antagonize proinflammatory response of IL-17 during cutaneous tuberculosis.
J Inflamm Res. 2018;28;11:… Regulatory T cells antagonize proinflammatory response of …

The role of helper T cells in psoriasis

P Hu, M Wang, H Gao, A Zheng, J Li, D Mu… - Frontiers in …, 2021 - frontiersin.org
IL-17 and IL-22 may mediate distinct downstream pathways that contribute to the psoriatic
phenotype: IL-17 is more pro-inflammatory than IL-22, while … anti-IL-17 receptor antagonist (IL-…

The IL-23/IL-17 pathway in inflammatory skin diseases: from bench to bedside

T Liu, S Li, S Ying, S Tang, Y Ding, Y Li, J Qiao… - Frontiers in …, 2020 - frontiersin.org
… subset of CD4 + T cells and are the major source of IL-17 (5). … patients with psoriasis with
latent tuberculosis infection (100). … of the Th17 cells and regulatory T (Treg) cells are elevated in …

Elevated IL-6R on CD4+ T cells promotes IL-6 driven Th17 cell responses in patients with T1R leprosy reactions

C Saini, RK Srivastava, M Tarique, S Kurra… - Scientific Reports, 2020 - nature.com
… establishes that pathogenic Th17 cells produce IL-17 in an IL-6 … of pro-inflammatory cells
called as Th17 which secrete IL-17 has … tuberculosis and M. leprae 34,35 . IL-6 is a pleiotropic …

Allies or enemies? The effect of regulatory T cells and related T lymphocytes on the profibrotic environment in bleomycin-injured lung mouse models

M Seyran, S Melanie, S Philip, G Amiq… - Clinical and experimental …, 2023 - Springer
… It is a pro-inflammatory cytokine produced mainly by CD4 + Th17 … could play a role in
counteracting bleomycin-induced lung injury in the bleomycin mouse model and that IL-17 levels …

Effects of regulatory T cells on macrophage inflammatory responses to Streptococcus pneumoniae

GS Szylar - 2020 - discovery.ucl.ac.uk
… human Treg cells reduce macrophage production of proinflammatory cytokines in … IL-17
and IFNα also aid neutrophil and macrophage function. CD4+ T cell numbers increase through