Toward an understanding of regulatory T cells in COVID19: a systematic review

M Rahimzadeh, N Naderi - Journal of Medical Virology, 2021 - Wiley Online Library
… We systematically searched electronic databases (PubMed, … in severe COVID-19 patients.
This finding underlines the hypothesis that Tregs play a role in the pathogenesis of COVID-19. …

[HTML][HTML] The role of CD4+ FoxP3+ regulatory T cells in the immunopathogenesis of COVID-19: implications for treatment

Y Wang, J Zheng, MS Islam, Y Yang… - International journal of …, 2021 - ncbi.nlm.nih.gov
… -mediated immune responses against SARS-CoV-2 in the early stage of infection as well
as dampening the excessive inflammation in severe COVID-19 patients in the late stage. …

[HTML][HTML] Regulatory T cells in COVID-19

H Wang, Z Wang, W Cao, Q Wu, Y Yuan… - Aging and …, 2021 - ncbi.nlm.nih.gov
… ratio and the subsequent systemic inflammation may contribute to the pathogenesis of …
In severe COVID-19 patients, T cells are highly activated but Foxp3 expression is inhibited, …

Deciphering the COVID19 cytokine storm: systematic review and meta‐analysis

R Mulchandani, T Lyngdoh… - European journal of …, 2021 - Wiley Online Library
Severe COVID-19 is characterized by significantly increased levels of pro-inflammatory
cytokines and reduced T lymphocytes. … of the COVID-19 immunopathogenesis which is largely …

[HTML][HTML] COVID-19: immunopathogenesis and Immunotherapeutics

L Yang, S Liu, J Liu, Z Zhang, X Wan… - Signal transduction and …, 2020 - nature.com
… of patients with COVID-19, especially in severe cases. CD69, … + T cells of patients, and
virus-specific T cells from severe … stem cell (MSC)-based therapy, regulatory T (Treg) cell-based …

T-cell dysregulation in COVID-19

B Kalfaoglu, J Almeida-Santos, CA Tye, Y Satou… - Biochemical and …, 2021 - Elsevier
… in severe COVID-19 patients. This article will show the evidence of T-cell dysregulation in
severe COVID-19 … including T-helper type 2 (Th2) and regulatory T-cells (Treg). IL-10 can …

The role of dysregulated immune responses in COVID-19 pathogenesis

S Tahaghoghi-Hajghorbani, P Zafari, E Masoumi… - Virus research, 2020 - Elsevier
… observed in the severity of the COVID-19 pathogenesis. … T cells leads to loss an efficient
immune response. Interestingly, the regulatory T cells (CD4+CD25+FOXP3+) and suppressor T

[HTML][HTML] Overview of the pathogenesis of COVID19

C Li, Q He, H Qian, J Liu - … and Therapeutic Medicine, 2021 - spandidos-publications.com
… aimed to systematically review the available literature on the … may serve a fundamental role
in severe COVID-19. Although … Th1/Th2 and Th17/regulatory T cells in COVID-19 may be a …

Immunology, immunopathogenesis and immunotherapeutics of COVID-19; an overview

LM Khosroshahi, M Rokni, T Mokhtari… - International …, 2021 - Elsevier
… 2019 (COVID-19) infection which is caused by severe acute … are major components of
COVID-19 pathogenesis. The former … of NK and CD8 + T cells in COVID-19 patients. This was …

… and leukocyte changes in mild versus severe SARS-CoV-2 infection: Review of 3939 COVID-19 patients in China and emerging pathogenesis and therapy concepts

J Wang, M Jiang, X Chen… - Journal of Leucocyte …, 2020 - academic.oup.com
Regulatory T cells (Tregs) play a critical role in dampening an excessive inflammatory
response as well as in antiviral immune responses. Therefore, Tregs may be central to …