… of renal damage in patients affected by primary aldosteronism … between primary aldosteronism
and renal damage through a … primary aldosteronism, suggesting that the observed effects …

… There are profound consequences of the high prevalence of PA, documented in the PAPY
Study (27) and confirmed in multiple surveys of selected cohorts (33–37) and in studies …

… In the Prevalence of Primary Aldosteronism in hYpertension (PAPY) Study, patients … rate
of primary aldosteronism found in this study could result from an accumulation of aldosterone-…

… and sustained aldosterone excess has deleterious effects on … and renal outcomes observed
in primary aldosteronism … sodium intake and chronic renal impairment can lower renin levels. …

… Herein, we review evidence indicating that primary aldosteronism is a prevalent syndrome
that is … As a result, and as our understanding of the prevalence of primary aldosteronism grew, …

… Aldosterone effects on renal injury were summarized in Figure 3A. Results of our present
study … ratio and abundant MR nuclear immunolocalization in renal tubules in PA than EH. As …

… Primary aldosteronism (PA) is a condition that is a result of … effect of mineralocorticoid receptor
activation by aldosterone … However, the PAPY study found that plasma aldosterone, BMI, …

… G, Letizia C, Maccario M, Mannelli M, Matterello MJ, et al; PAPY Study Participants.
Renal damage in primary aldosteronism: results of the PAPY study. Hypertension. 2006;48:232–238. …

… Our findings also extend the results of prior studies implicating primary aldosteronism in the
pathogenesis of a substantial proportion of hypertension and downstream cardiovascular risk…

… the blood samples after 60 ​min of quiet supine or sitting rest (Class of Recommendation
II, Level of Evidence B), the conditions that provided optimal results in the PAPY Study [9]. …