COVID‐19 typically exhibits respiratory illness. Unexpectedly, emerging clinical reports
indicate that neurological symptoms continue to rise, suggesting detrimental effects of SARS‐
CoV‐2 on the central nervous system (CNS). Here, we show that a Düsseldorf isolate of
SARS‐CoV‐2 enters 3D human brain organoids within 2 days of exposure. We identified
that SARS‐CoV‐2 preferably targets neurons of brain organoids. Imaging neurons of …