Tracing the first hematopoietic stem cell generation in human embryo by single-cell RNA sequencing

Y Zeng, J He, Z Bai, Z Li, Y Gong, C Liu, Y Ni, J Du… - Cell research, 2019 - nature.com
… Tracing the emergence of the first hematopoietic stem cells (HSCs) in human embryos,
particularly … Here, using single-cell RNA sequencing, we constructed the first genome-scale gene …

The glioma stem cell model in the era of single-cell genomics

ML Suva, I Tirosh - Cancer cell, 2020 - cell.com
… differ in their cellular architecture and relate the observed cellular states to established GSC
… a set of single-cell informed definitions as a framework for our understanding of the cellular

Single-cell biology: beyond the sum of its parts

AF Schier - Nature Methods, 2020 - nature.com
… In another study, combined single-cell methylome and RNA sequencing suggested that
aging muscle stem cells do not have a methylation clock but instead show uncoordinated …

… Wharton's jelly mesenchymal stem cells show unique gene expression compared with bone marrow mesenchymal stem cells using single-cell RNA-sequencing

AN Barrett, CY Fong, A Subramanian, W Liu… - Stem Cells and …, 2019 - liebertpub.com
stem cells (hWJSCs) isolated from the human umbilical cord are a unique population of
mesenchymal stem cells (… these two stem cell types using single-cell RNA sequencing (scRNA-…

Differentiation of transplanted haematopoietic stem cells tracked by single-cell transcriptomic analysis

F Dong, S Hao, S Zhang, C Zhu, H Cheng, Z Yang… - … cell biology, 2020 - nature.com
… Diffusion map analysis of our single-cell haematopoietic stem and progenitor cell data showed
… 22 , which indicates that our sequencing data is of high quality (Extended Data Fig. 2a–c). …

Plant stem-cell organization and differentiation at single-cell resolution

JW Satterlee, J Strable… - Proceedings of the …, 2020 - National Acad Sciences
stem cells in shoot apical meristems (SAMs), which continuously produce new aboveground
organs. We used single-cell RNA sequencing (… stem-cell niche and its differentiating cellular

Singlecell RNA sequencing technologies and applications: A brief overview

D Jovic, X Liang, H Zeng, L Lin, F Xu… - Clinical and …, 2022 - Wiley Online Library
stem cells (ESCs) and induced pluripotent stem cells (iPSCs) 3D models. The studies
performed on mouse models revealed several important aspects of the pancreas development. …

Single-cell transcriptomes of the regenerating intestine reveal a revival stem cell

A Ayyaz, S Kumar, B Sangiorgi, B Ghoshal, J Gosio… - Nature, 2019 - nature.com
… Thus, whether cellular plasticity or distinct cell populations … Here we applied single-cell
RNA sequencing to profile the … -induced quiescent cell type that we term the revival stem cell (…

[HTML][HTML] Single-cell analysis of regional differences in adult V-SVZ neural stem cell lineages

D Mizrak, HM Levitin, AC Delgado, V Crotet, J Yuan… - Cell reports, 2019 - cell.com
… We performed large-scale single-cell RNA sequencing to … large-scale, single-cell profiling
of all V-SVZ cell types in the … without cell sorting and identify cell subtypes in V-SVZ stem cell

Applications of single-cell sequencing in cancer research: progress and perspectives

Y Lei, R Tang, J Xu, W Wang, B Zhang, J Liu… - Journal of hematology & …, 2021 - Springer
… has revolutionized our understanding of the biological characteristics and … single-cell
sequencing technologies and recent cancer research progress obtained by single-cell sequencing, …