Cytokine storm: the primary determinant for the pathophysiological evolution of COVID-19 deterioration

R Chen, Z Lan, J Ye, L Pang, Y Liu, W Wu… - Frontiers in …, 2021 - frontiersin.org
… deterioration and death in COVID-19 patients. … cytokine storms promote the deterioration
of COVID-19. Here, we outline the pathophysiological processes through which cytokine storms

[HTML][HTML] Severe immunosuppression and not a cytokine storm characterizes COVID-19 infections

KE Remy, M Mazer, DA Striker, AH Ellebedy… - JCI insight, 2020 - ncbi.nlm.nih.gov
… The purpose of this study was to determine whether critically ill COVID-19 patients have an
exaggerated proinflammatory cytokine storm versus an immunosuppressive immunological …

COVID-19 cytokine storm: the interplay between inflammation and coagulation

RJ Jose, A Manuel - The Lancet Respiratory Medicine, 2020 - thelancet.com
… [TNF], IL-6, and IL-1β) results in what has been described as a cytokine storm, leading to an
… failure, and eventually death when the high cytokine concentrations are unabated over time.…

COVID-19 cytokine storm: targeting the appropriate cytokine

RQ Cron - The Lancet Rheumatology, 2021 - thelancet.com
… in improving COVID-19IL-6 inhibition in the treatment of COVID-19 cytokine storm syn
drome. 7 This single-centre, observational study of patients admitted to hospital with COVID-19, …

On the alert for cytokine storm: immunopathology in COVID19

LA Henderson, SW Canna, GS Schulert… - Arthritis & …, 2020 - Wiley Online Library
… Absent the opportunity to enroll patients in one of these studies, we would consider
immunosuppression in patients with COVID-19 who have incipient cytokine storm. Ideally, treatment …

Cytokine storm in COVID-19—immunopathological mechanisms, clinical considerations, and therapeutic approaches: the REPROGRAM consortium position paper

S Bhaskar, A Sinha, M Banach, S Mittoo… - Frontiers in …, 2020 - frontiersin.org
… between cytokine storm and severe COVID-19 complications, we propose a cytokine
storm-based diagnosis and management workflow for patients with or suspected of COVID-19 (…

A glimpse into the eye of the COVID-19 cytokine storm

K Kuppalli, AL Rasmussen - EBioMedicine, 2020 - thelancet.com
… interpretations of COVID-19-specific effects on inflammatory cytokine production and immune
… with cytokine storms and COVID-19 severity, further data from other cohorts of COVID-19

[HTML][HTML] Cytokine storm in COVID-19:“when you come out of the storm, you won't be the same person who walked in”

V Castelli, A Cimini, C Ferri - Frontiers in immunology, 2020 - frontiersin.org
… distress syndrome is the so-called “cytokine storm,” which is an aberrant response from the
cytokines/chemokines. In this review, we will discuss the role of cytokine storm in COVID-19

The cytokine storm of COVID-19: a spotlight on prevention and protection

L Pearce, SM Davidson, DM Yellon - Expert Opinion on …, 2020 - Taylor & Francis
… As seen in the influenza pandemic of 1918, it has been suggested that a cytokine storm of
… which target the COVID-19 induced cytokine storm. As this is not exclusive to COVID-19, we …

Weathering the cytokine storm in COVID-19: therapeutic implications

G Iannaccone, R Scacciavillani, MG Del Buono… - Cardiorenal …, 2020 - karger.com
cytokine release in response to viral infection, a condition known as cytokine release syndrome
(CRS) or cytokine storm… to ARDS and MOF in COVID-19, thus endorsing the hypothesis …