The evolving facets of bacterial vaginosis: implications for HIV transmission

LR McKinnon, SL Achilles, CS Bradshaw… - AIDS research and …, 2019 - liebertpub.com
… , including protection against HIV infection. Optimal—… symptoms, lack of genital inflammation,
and decreased HIV … vaginal symptoms and/or genital inflammation and/or increased HIV

Phylogenies in ART: HIV reservoirs, HIV latency and drug resistance

A Bandera, A Gori, M Clerici, M Sironi - Current opinion in pharmacology, 2019 - Elsevier
… In line with this possibility, HIV evolutionary rates similar to those observed in untreated
patients were reported for viral DNA or RNA obtained from post-mortem tissues of ART-treated …

Origins and evolutionary consequences of ancient endogenous retroviruses

WE Johnson - Nature Reviews Microbiology, 2019 - nature.com
… , driving the evolution of host genes … origins, their diversity and their relationships to
retroviruses and discusses the potential for ERVs to reveal virus–host interactions on evolutionary

Evolutionary causes and consequences of bacterial antibiotic persistence

E Bakkeren, M Diard, WD Hardt - Nature Reviews Microbiology, 2020 - nature.com
… In this Review, we discuss the evolutionary forces that may drive the selection for antibiotic
… We then discuss the consequences of antibiotic persistence on pathogen evolution. …

Rampant C→ U hypermutation in the genomes of SARS-CoV-2 and other coronaviruses: causes and consequences for their short-and long-term evolutionary …

P Simmonds - Msphere, 2020 - Am Soc Microbiol
… be driven by a host APOBEC-like editing process has profound implications for understanding
their short- and long-term evolution. Repeated cycles of mutation and reversion in favored …

Why and where an HIV cure is needed and how it might be achieved

T Ndung'u, JM McCune, SG Deeks - Nature, 2019 - nature.com
Despite considerable global investment, only 60% of people who live with HIV currently
receive antiretroviral therapy. The sustainability of current programmes remains unknown and …

Prisoners of war—host adaptation and its constraints on virus evolution

P Simmonds, P Aiewsakun, A Katzourakis - Nature Reviews …, 2019 - nature.com
evolution that aims to reconcile these conflicting aspects of virus evolutionary histories over
different evolutionary … represents the primary driver of the longer-term evolution of viruses. …

[图书][B] The origins of AIDS

J Pepin - 2021 - books.google.com
… of HIV/AIDSeffect to fuel the spread of the virus from its origins in Léopoldville to the rest
of Africa, the Caribbean and ultimately worldwide. This is an essential perspective on HIV/AIDS

Research priorities for an HIV cure: international AIDS society global scientific strategy 2021

…, International AIDS Society (IAS) Global Scientific … - Nature medicine, 2021 - nature.com
… protect cells from infection, also holds promise for future HIV cure strategies. In this Review,
we discuss advances related to HIV cure in the last 5 years, highlight remaining knowledge …

HIV rebound is predominantly fueled by genetically identical viral expansions from diverse reservoirs

MA De Scheerder, B Vrancken, S Dellicour, T Schlub… - Cell host & …, 2019 - cell.com
… To unravel the source of rebounding viruses, we conducted a large-scale HIV-STAR (HIV-1
sequencing before analytical treatment interruption to identify the anatomically relevant HIV