Effects of age, sex, serostatus, and underlying comorbidities on humoral response post-SARS-CoV-2 Pfizer-BioNTech mRNA vaccination: a systematic review

KI Notarte, AT Ver, JV Velasco, A Pastrana… - Critical reviews in …, 2022 - Taylor & Francis
… -individual heterogeneity in post-vaccine immune response has been increasingly observed
… that the decline in adaptive immunity results in dramatically reduced vaccine responses and …

[HTML][HTML] Age-associated changes in the impact of sex steroids on influenza vaccine responses in males and females

T Potluri, AL Fink, KE Sylvia, S Dhakal, MS Vermillion… - npj Vaccines, 2019 - nature.com
effects of age on the adaptive immune response to vaccinesimmune responses to influenza
infection and vaccination, in … , age, and sex steroid hormones impact the humoral immune

The immune system and its dysregulation with aging

L Müller, S Di Benedetto, G Pawelec - … cell biology of ageing: Part II clinical …, 2019 - Springer
effects of aging on the most important components of the immune system. It considers the …
or at least contribute to the lowered responses to new pathogens and to poor vaccination

Aging in COVID-19: Vulnerability, immunity and intervention

Y Chen, SL Klein, BT Garibaldi, H Li, C Wu… - Ageing research …, 2021 - Elsevier
… Much remains to be learned about the immune responses to SARS-CoV-2 infection. We …
assessment of how aging impacts the immune response to the virus and possibly the vaccine. …

[HTML][HTML] Effects of regular physical activity on the immune system, vaccination and risk of community-acquired infectious disease in the general population: systematic …

SFM Chastin, U Abaraogu, JG Bourgois, PM Dall… - Sports Medicine, 2021 - Springer
… , enhances the first line of defence of the immune system, and increases the potency of
vaccination. … which in turn affects both the immune system and inflammatory responses [87]. …

An aged immune system drives senescence and ageing of solid organs

MJ Yousefzadeh, RR Flores, YI Zhu, ZC Schmiechen… - Nature, 2021 - nature.com
… -dependent changes limit the effectiveness of vaccinations, … of the aged immune system
to systemic ageing, independent … by qRT–PCR reactions using 20 μl reaction volumes and a …

Vaccines to prevent infectious diseases in the older population: immunological challenges and future perspectives

A Wagner, B Weinberger - Frontiers in immunology, 2020 - frontiersin.org
Age-associated changes of the immune system are … used vaccines in older age. Efficacy of
standard influenza … to chronological age, which influence immune responses to vaccination. …

Age-specific differences in the dynamics of protective immunity to influenza

S Ranjeva, R Subramanian, VJ Fang… - Nature …, 2019 - nature.com
… that influenza antibody responses shift focus with age from the … increase with age 40,41 ,
and that vaccination with a partially … observations of the immune response can help separate …

Reduced magnitude and durability of humoral immune responses to COVID-19 mRNA vaccines among older adults

MA Brockman, F Mwimanzi, HR Lapointe… - The Journal of …, 2022 - academic.oup.com
… To examine immune response durability, we reassessed humoral outcomes 3 months … Our
results thus identify age as the most critical and consistent variable modulating the magnitude …

Sex differences in vaccine-induced humoral immunity

S Fischinger, CM Boudreau, AL Butler… - Seminars in …, 2019 - Springer
… Specifically, genetics, race, age, social background, and sex … the immune system, have also
been shown to impact vaccine … In summary, MMR vaccination induces divergent responses