… There are limited neuroprotective treatment options for … care unit with adherence to Class I
and IIa recommendations for … pilot study, trials that focused on ischemic stroke were used as a …

… stroke studies that sought to apply discoveries from basic research to clinical treatment plans,
particularly in the area of neuroprotection, fell … research and the failure of clinical trials. Our …

… no neuroprotective drug has been clinically proven to be effective so far. The fundamental
reasons for the failure are the difficulty for the neuroprotective … This pilot study provides Class I …

… of learning, memory and cognitive function in post-stroke … neuroprotective effects when
treatment is initiated within 24 h of stroke in both experimental and clinical stroke studies …

… focus on (1) the therapeutic potential of exosomes in stroke treatment, (2) the optimization
… Toward wisdom from failure: Lessons from neuroprotective stroke trials and new therapeutic …

… have failed, partly due to ambitious outcome measures. … randomized clinical trial—The Head
Positioning in Acute Stroke Trial (… new neuroprotective adjunctive therapy for acute ischemic …

… here shows strong neuroprotective actions with minimal side … increase the therapeutic safety
of this class by improving … trials in stroke or TBI using NMDAR antagonists either failed to …

… moderate stroke should be the best target of neuroprotective … time from the onset of stroke to
RIC treatment was within 4 h (… most studies regarding neuroprotective therapy for stroke was …

… trials in stroke. However, a recent study in comorbid animals showed that non-conditioned
MSCs failed to exert neuroprotective … into a more effective therapy for stroke. Here we show for …

… in preclinical models of neuroprotection after stroke and is an … failures than the promise it
holds for the future of therapeutic … We will not cover these proteomic studies in detail here, as …