… estimated using DNA methylation profiles, the foundation of pan-tissue epigenetic … universal
pan-mammalian clocks, using 11,754 methylation arrays from our Mammalian Methylation …

… Since such pan-tissue epigenetic clocks have been … -mammalian clocks that measure age
in all mammalian species. To address this, we generated data using 11,754 methylation arrays…

… -types derived from 128 mammalian species. From these, we … methylation levels change
with age across mammalian … mammalian developmental processes and implicated in age-…

… mammalian methylation array to profile 37,492 cytosine-guanine sites (CpGs) across highly
conserved stretches of DNA in … , which reports the universal chromatin states in humans 68 . …

… DNA methylation profiles (n = 15,456) from 348 mammalian … Using unsupervised clustering
across all samples, we … maximum life span, adult weight, age, sex, and human mortality risk. …

… the genetic code, or if DNA methylation is non-universal and specific to every evolutionary
… DNA methylation patterns can be different in different organisms of a species or even tissues …

… types at loci that are highly conserved between mammalian … changes in DNA methylation
that accompany equine aging and … ) and methylation across tissue types, we generated DNA …

… of multiple mammalian … universal chromatin state map, which defined 16 groups of chromatin
states from 1,032 experiments mapping chromatin marks across 127 human cell and tissue …

… age estimation using a custom mammalian DNA methylation … on age-related methylation
changes for comparable tissues … have greater accuracy than such universal clocks. Although …

… from 348 mammalian species, we derive DNA methylation (… universal sex predictors grounded
in CpG methylation levels … While we offer these tissue predictors to the community as tools …