Influenza infection, SARS, MERS and COVID-19: cytokine storm–the common denominator and the lessons to be learned

VA Ryabkova, LP Churilov, Y Shoenfeld - Clinical Immunology, 2021 - Elsevier
… To describe this phenomenon, the term “cytokine storm” has … cytokine storm is considered
as the result of the disrupted immune response to the initial insult, the range of the clinical

Current treatment options and safety considerations when treating adult-onset Still's disease

G Cavalli, N Farina, C Campochiaro… - Expert Opinion on …, 2020 - Taylor & Francis
… the available clinical data in order to provide useful information to clinicians about the …
shock and, more recently, to the cytokine storm and hyper-inflammation developing in severe …

[HTML][HTML] Cytokine storm and immunomodulation in COVID-19

P Rangappa - Indian Journal of Critical Care Medicine: Peer …, 2021 - ncbi.nlm.nih.gov
… It is known for its capacity to clear the infective organism from the body in preclinical as well
as clinical studies. In the clinical trials conducted, Mw leads to early clinical recovery in most …

[HTML][HTML] Calming the storm: natural immunosuppressants as adjuvants to target the cytokine storm in COVID-19

AE Peter, BV Sandeep, BG Rao… - Frontiers in …, 2021 - frontiersin.org
… Although the clinical presentations of cytokines vary for different diseases, they are … , luteolin
is an important natural agent for consideration as a potential therapeutic that can be further …

Hemoperfusion as a potential treatment for critically ill COVID-19 patients with cytokine storm

K Shadvar, A Tagizadiyeh, AA Gamari… - Blood …, 2021 - karger.com
clinical features and cytokine profile of critically ill patients with COVID-19 in Wuhan, China,
and suggested that a cytokine storm … Severe SARSCoV-2 infections: practical considerations

Immune immunomodulation in coronavirus disease 2019 (COVID-19): strategic considerations for personalized therapeutic intervention

MW Hall, I Joshi, L Leal, EE Ooi - Clinical Infectious Diseases, 2022 - academic.oup.com
… There is leakage of proinflammatory cytokines such as IL-6, … and systemic levels of suppressive
cytokines such as IL-10 … cytokine levels is frequently referred to as a “cytokine storm,” the …

[HTML][HTML] Cytokine storm and histopathological findings in 60 cases of COVID-19-related death: from viral load research to immunohistochemical quantification of major …

P Frisoni, M Neri, S D'Errico, L Alfieri… - … Science, Medicine and …, 2022 - Springer
… the expression of multiple cytokines (IL-1β, IL-6, IL-10, IL-15, … strong and diffuse
immunoreactivity for IL-6 and IL-15 in the … Current evidence suggests that a cytokine storm is the …

Underlying vulnerabilities to the cytokine storm and adverse COVID-19 outcomes in the aging immune system

LS Nidadavolu, JD Walston - The Journals of Gerontology …, 2021 - academic.oup.com
… damage, high levels of inflammatory cytokines damage and create gaps between … cytokine
storm also trigger multiple and varied systemic signs and symptoms highly relevant to clinical

The cytokine storms of COVID-19, H1N1 influenza, CRS and MAS compared. Can one sized treatment fit all?

G Morris, CC Bortolasci, BK Puri, W Marx, A O'Neil… - Cytokine, 2021 - Elsevier
cytokine storm A proposed early event in the development of the COVID-19 cytokine storm
the presence of high levels of proinflammatory cytokines chemokines and ROS species. Such …

[HTML][HTML] From anti-SARS-CoV-2 immune response to the cytokine storm via molecular mimicry

D Kanduc - Antibodies, 2021 - mdpi.com
… scientific-–clinical relevance in light of the consideration that, … activating so-called ‘cytokine
storms’ and cause physical occlusion … the etiology of the cytokine storm syndromes. Moreover, …