Genetics of congenital heart disease

K Williams, J Carson, C Lo - Biomolecules, 2019 - mdpi.com
Congenital heart disease (CHD) is one of the most common birth defects. Studies in animal
models and humans have indicated a genetic etiology for CHD. About 400 genes have been …

Genomic frontiers in congenital heart disease

SU Morton, D Quiat, JG Seidman… - Nature Reviews …, 2022 - nature.com
The application of next-generation sequencing to study congenital heart disease (CHD) is
increasingly providing new insights into the causes and mechanisms of this prevalent birth …

Adult congenital heart disease: past, present and future

M Brida, MA Gatzoulis - Acta Paediatrica, 2019 - Wiley Online Library
The diagnosis and management of congenital heart disease (CHD), the most common inborn
defect, has been a tremendous success story of modern medicine. In the 1950s, survival of …

Environmental risk factors for congenital heart disease

JI Kalisch-Smith, N Ved… - Cold Spring Harbor …, 2020 - cshperspectives.cshlp.org
Congenital heart disease (CHD) has many forms and a wide range of causes… heart.” Fifty
years later, the pioneering cardiac pathologist Maud Abbott wrote that congenital heart disease (…

Survival in children with congenital heart disease: have we reached a peak at 97%?

Z Mandalenakis, KW Giang, P Eriksson… - … of the American Heart …, 2020 - Am Heart Assoc
… cohort study the survival in children with congenital heart disease born until the late 2010s.
congenital heart disease compared with matched controls without congenital heart disease

Molecular genetics and complex inheritance of congenital heart disease

NS Diab, S Barish, W Dong, S Zhao, G Allington, X Yu… - Genes, 2021 - mdpi.com
Congenital heart disease (CHD) is a collective diagnosis for structural malformations of the
heart and great vessels [1]. Individual lesions within CHD have been grouped into anatomic …

Genetic basis of human congenital heart disease

SN Nees, WK Chung - Cold Spring Harbor perspectives …, 2020 - cshperspectives.cshlp.org
Congenital heart disease (CHD) is the most common major congenital anomaly with an
incidence of ∼1% of live births and is a significant cause of birth defect–related mortality. The …

Mental health disorders in children with congenital heart disease

VJ Gonzalez, RT Kimbro, KE Cutitta, JC Shabosky… - …, 2021 - publications.aap.org
BACKGROUND: Data on anxiety, depression, and attention-deficit/hyperactivity disorder (ADHD)
are lacking for youth with congenital heart disease (CHD), particularly those with …

Heart failure related to adult congenital heart disease: prevalence, outcome and risk factors

S Arnaert, P De Meester, E Troost, W Droogne… - ESC heart …, 2021 - Wiley Online Library
Aims Information on the prevalence, outcome and factors associated with heart failure in
patients with adult congenital heart disease (CHD) (ACHD‐HF) is lacking. We aimed at …

The ESC clinical practice guidelines for the management of adult congenital heart disease 2020

H Baumgartner, J De Backer - 2020 - academic.oup.com
congenital heart disease (CHD) now present in increasing numbers at advanced ages, including
the elderly, the term ‘grown-up congenital heart disease… adult congenital heart disease (…