Confronting the controversy: interleukin-6 and the COVID-19 cytokine storm syndrome

LYC Chen, RL Hoiland, S Stukas… - European …, 2020 - Eur Respiratory Soc
… of COVID-19 in our own centre, when IL-6 was being measured for research purposes rather
than clinical care, we used the following criteria for COVID-CSS: 1) COVID-19 pneumonia …

The cytokine storm of COVID-19: a spotlight on prevention and protection

L Pearce, SM Davidson, DM Yellon - Expert Opinion on …, 2020 - Taylor & Francis
… As seen in the influenza pandemic of 1918, it has been suggested that a cytokine storm of
… which target the COVID-19 induced cytokine storm. As this is not exclusive to COVID-19, we …

On the alert for cytokine storm: immunopathology in COVID19

LA Henderson, SW Canna, GS Schulert… - Arthritis & …, 2020 - Wiley Online Library
… Absent the opportunity to enroll patients in one of these studies, we would consider
immunosuppression in patients with COVID-19 who have incipient cytokine storm. Ideally, treatment …

COVID-19 infection: an overview on cytokine storm and related interventions

S Montazersaheb, SM Hosseiniyan Khatibi, MS Hejazi… - Virology journal, 2022 - Springer
… decrease the outbreak of COVID-19 and mitigate its symptoms [… COVID-19 may be a promising
intervention for COVID-19-… understanding of cytokines-induced alterations in COVID-19, …

Tackling the cytokine storm in COVID-19, challenges and hopes

SM Abdin, SM Elgendy, SK Alyammahi, DW Alhamad… - Life Sciences, 2020 - Elsevier
… interference with the cytokine storm as a therapeutic approach to tackle COVID-19. In this …
into the cytokine storm phenomena as one of the key players to COVID-19 aggressiveness and …

Critical determinants of cytokine storm and type I interferon response in COVID-19 pathogenesis

S Ramasamy, S Subbian - Clinical microbiology reviews, 2021 - Am Soc Microbiol
… in COVID-19. This review describes critical host and viral factors underpinning the
inflammatory “cytokine storm” induction and IFN antagonism during COVID-19 pathogenesis. …

[HTML][HTML] Cytokine storms: understanding COVID-19

N Mangalmurti, CA Hunter - Immunity, 2020 - cell.com
… a bona fide cytokine storm underlies COVID-19 pathologies, but … Perhaps research on
COVID-19 will provide impetus to … of strategies that target cytokines, complement, and coagulation …

The possible pathophysiology mechanism of cytokine storm in elderly adults with COVID-19 infection: the contribution of “inflame-aging”

GH Meftahi, Z Jangravi, H Sahraei, Z Bahari - Inflammation Research, 2020 - Springer
… Then, a cytokine storm can induce edematous, ARDS, … till now why cytokine storm induces
in only COVID-19 elderly patients… between cytokine storm in elderly patients of COVID-19 and “…

COVID-19 cytokine storm syndrome: a threshold concept

LYC Chen, TTT Quach - The Lancet Microbe, 2021 - thelancet.com
… The COVID-19 pandemic has placed the … of COVID-19 cytokine storm syndrome (COVID-19-CSS).
Early in the pandemic, high levels of inflammatory cytokines such as interleukin-6 (IL-6

Cytokine storm in COVID-19:“when you come out of the storm, you won't be the same person who walked in”

V Castelli, A Cimini, C Ferri - Frontiers in immunology, 2020 - frontiersin.org
… distress syndrome is the so-called “cytokine storm,” which is an aberrant response from the
cytokines/chemokines. In this review, we will discuss the role of cytokine storm in COVID-19