Blood DNA methylation and COVID-19 outcomes

J Balnis, A Madrid, KJ Hogan, LA Drake, HC Chieng… - Clinical …, 2021 - Springer
… We hypothesized that: (1) DNA methylation regions would differ in patients with COVID-19
patterns of differential DNA methylation in blood, we used the COVID-19 specific GRAM risk …

An epigenome‐wide DNA methylation study of patients with COVID19

S Zhou, J Zhang, J Xu, F Zhang, P Li… - Annals of human …, 2021 - Wiley Online Library
… to shed light on the DNA methylation changes in healthy subjects and patients with different
severities of COVID-19 to explore novel targets and effective methods for treating COVID-19. …

Whole blood DNA methylation analysis reveals respiratory environmental traits involved in COVID-19 severity following SARS-CoV-2 infection

G Barturen, E Carnero-Montoro… - Nature …, 2022 - nature.com
COVID-19 severity, here we present a DNA methylation EWAS (epigenome wide association
analysis) combined with DNA … of COVID-19 pathogenic mechanisms, the DNA methylation

Genome-wide DNA methylation profiling of peripheral blood reveals an epigenetic signature associated with severe COVID-19

MJ Corley, APS Pang, K Dody, PA Mudd… - Journal of leukocyte …, 2021 - academic.oup.com
… Notably, among the differentially methylated loci associated with severe COVID-19, we … in
the type I IFN response associated with severe COVID-19 (Fig. 1E) including first line antiviral …

Genetic alteration, RNA expression, and DNA methylation profiling of coronavirus disease 2019 (COVID-19) receptor ACE2 in malignancies: a pan-cancer analysis

P Chai, J Yu, S Ge, R Jia, X Fan - Journal of hematology & oncology, 2020 - Springer
… not compare global DNA methylation level of KICH. Instead, we compared DNA methylation
level of KICH across different tumor stages, and we found that the DNA methylation was not …

Epigenomics in COVID-19; the link between DNA methylation, histone modifications and SARS-CoV-2 infection

M Shirvaliloo - Epigenomics, 2021 - Future Medicine
… [1], such as coronavirus disease 2019 (COVID-19). Known to … susceptibility of the pulmonary
tissue to COVID-19 [2] and a … of innate immunity against COVID-19, particularly in male …

A machine learning approach utilizing DNA methylation as an accurate classifier of COVID-19 disease severity

S Bowler, G Papoutsoglou, A Karanikas… - Scientific Reports, 2022 - nature.com
… sites with the power to discern individuals with severe COVID-19 disease. The … DNA
methylation in COVID-19 disease pathology and serve as a platform to inform future COVID-19

Longitudinal study of DNA methylation and epigenetic clocks prior to and following test-confirmed COVID-19 and mRNA vaccination

APS Pang, AT Higgins-Chen, F Comite, I Raica… - Frontiers in …, 2022 - frontiersin.org
… of longitudinal DNA methylation studies of COVID-19 and mRNA COVID-19 vaccination, we
provide discovery findings that are compelling regarding specific DNA methylation changes …

Epigenetic mechanisms regulating COVID-19 infection

S Chlamydas, AG Papavassiliou, C Piperi - Epigenetics, 2021 - Taylor & Francis
… in regulating the ACE2 X-linked gene expression in the context of COVID-19. DNA
methylation and H3K4 methylation at the promoter of the gene have been found to influence its …

Identification of COVID-19-associated DNA methylation variations by integrating methylation array and scRNA-Seq data at cell-type resolution

G Wang, Z Xiong, F Yang, X Zheng, W Zong, R Li… - Genes, 2022 - mdpi.com
… by exploring the COVID-19 DNA methylation variation at the … single-cell DNA methylation
variations in COVID-19 patients by … the methylation variations in the whole blood of COVID-19