Immune-mediated approaches against COVID-19

HF Florindo, R Kleiner, D Vaskovich-Koubi… - Nature …, 2020 - nature.com
… the design of COVID-19 specific therapeutics and vaccines … of these prophylactic and
therapeutic approaches. This Review … -mediated approaches currently explored for COVID-19

Flavonoids: A complementary approach to conventional therapy of COVID-19?

J Solnier, JP Fladerer - Phytochemistry Reviews, 2021 - Springer
COVID-19, the highly contagious novel disease caused by … and therapeutic treatment options
for this new coronavirus … , to date, no antiviral therapeutics available that specifically target …

Nanotechnology for COVID-19: therapeutics and vaccine research

G Chauhan, MJ Madou, S Kalra, V Chopra, D Ghosh… - ACS …, 2020 - ACS Publications
… conventional therapeutic and vaccine designs. Several other approaches including advanced
nanomaterial and biomimetic approaches represent good potential usage in a COVID-19-…

Endothelial activation and dysfunction in COVID-19: from basic mechanisms to potential therapeutic approaches

Y Jin, W Ji, H Yang, S Chen, W Zhang… - … and targeted therapy, 2020 - nature.com
… endothelial activation and dysfunction participate in COVID-19 pathogenesis by altering the
integrity … during COVID-19 emphasizing the principal mediators and therapeutic implications. …

Cytokine storm in COVID-19—immunopathological mechanisms, clinical considerations, and therapeutic approaches: the REPROGRAM consortium position paper

S Bhaskar, A Sinha, M Banach, S Mittoo… - Frontiers in …, 2020 - frontiersin.org
… targeted for therapy. Leveraging expert opinion, emerging evidence, and a case-based
approach, … critical insights on cytokine storm from both a prognostic and therapeutic standpoint. …

Cellular and molecular pathways of COVID-19 and potential points of therapeutic intervention

JP Hussman - Frontiers in pharmacology, 2020 - frontiersin.org
… candidate therapeutics targeting molecular mediators of the COVID-19 hyperinflammatory …
health crisis and a pressing need for therapeutic approaches to contain the number of fatalities…

A strategic approach to COVID-19 vaccine R&D

L Corey, JR Mascola, AS Fauci, FS Collins - Science, 2020 - science.org
… With strong central leadership from the NIH, ACTIV could expeditiously discover and deliver
therapy for COVID-19. But, beyond this initial endeavor, the ACTIV format once established …

COVID-19 illness in native and immunosuppressed states: A clinical–therapeutic staging proposal

HK Siddiqi, MR Mehra - The journal of heart and lung transplantation, 2020 - jhltonline.org
… the therapeutic tactics employed in COVID-19. It is imperative that a structured approach to
… and reporting of this disease to facilitate therapeutic application and evaluate response. We …

The rheumatologist's role in COVID-19

RQ Cron, WW Chatham - The Journal of rheumatology, 2020 - jrheum.org
… investigation so that therapeutic approaches can be considered … approach to care for
COVID-19 patients with CSS, with the implicit understanding that deviations from this approach may …

A critical overview of computational approaches employed for COVID-19 drug discovery

EN Muratov, R Amaro, CH Andrade, N Brown… - Chemical Society …, 2021 - pubs.rsc.org
… finding COVID-19 drugs among approved therapeutics, most … several thousand of COVID-19
therapeutic clinical trials of … majority of trials of therapeutics for COVID-19 are not designed …