SARS-CoV-2/COVID-19: viral genomics, epidemiology, vaccines, and therapeutic interventions

M Uddin, F Mustafa, TA Rizvi, T Loney, H Al Suwaidi… - Viruses, 2020 - mdpi.com
… of resources that will help the scientific community access numerous types of databases
related to SARS-CoV-2 OMICs and approaches to therapeutics related to COVID-19 treatment. …

COVID-19: hemoglobin, iron, and hypoxia beyond inflammation. A narrative review

A Cavezzi, E Troiani, S Corrao - Clinics and practice, 2020 - mdpi.com
… A more comprehensive diagnostic/therapeutic approach to COVID-19 is proposed, includ- …
tissue iron overload in COVID-19; potential adjuvant therapeutic interventions, targeting the …

Drug development and medicinal chemistry efforts toward SARS‐coronavirus and Covid19 therapeutics

AK Ghosh, M Brindisi, D Shahabi… - …, 2020 - Wiley Online Library
… medicinal-chemistry approaches against SARS-CoV, MERS-CoV and COVID-19 targets. The
… development of effective therapies against COVID-19 and other pathogenic coronaviruses. …

COVID-19 vaccines: The status and perspectives in delivery points of view

JY Chung, MN Thone, YJ Kwon - Advanced drug delivery reviews, 2021 - Elsevier
… Potential vaccines and therapeutics against COVID-19 include repurposed drugs, … therapies
for COVID-19 to vaccination, principles and design considerations in COVID-19 vaccine …

[HTML][HTML] Natural history of COVID-19 and current knowledge on treatment therapeutic options

WG Dos Santos - Biomedicine & Pharmacotherapy, 2020 - Elsevier
therapy. The structure and target of some of the repurposed drugs evaluated for treatment of
COVID-19 is … drugs and other therapeutic approaches are presented and discussed below. …

The trinity of COVID-19: immunity, inflammation and intervention

MZ Tay, CM Poh, L Rénia, PA MacAry… - Nature Reviews …, 2020 - nature.com
coronavirus 2 (SARS-CoV-2) is the causative agent of the ongoing coronavirus disease 2019
(COVID-19… the implications of these approaches for potential therapeutic interventions that …

Immunotherapies for COVID-19: lessons learned from sepsis

KE Remy, SC Brakenridge, B Francois… - The Lancet …, 2020 - thelancet.com
… immunity in COVID-19 relative to sepsis argues for perhaps a different therapeutic approach.
… as an essential component of any therapeutic intervention, of equal importance to or …

Pathogenesis of multiple organ injury in COVID-19 and potential therapeutic strategies

M Lopes-Pacheco, PL Silva, FF Cruz… - Frontiers in …, 2021 - frontiersin.org
… to evaluate the safety and efficacy of therapeutic approaches for COVID-19. (A) Distribution
… (C) Distribution of 1,520 clinical trials based on therapeutic approaches under investigation: …

Clinical observation and management of COVID-19 patients

T Li, H Lu, W Zhang - Emerging microbes & infections, 2020 - Taylor & Francis
… of the COVID-19 cases. He introduces the team approach to manage COVID-19 patients.
For … ), low-dose short-course glucocorticoids therapy, among other approaches. The use of …

Is COVID-19 a new hematologic disease?

B Debuc, DM Smadja - Stem cell reviews and reports, 2021 - Springer
… The therapeutic strategies are only supportive. Immunomodulatory drugs … Thus, MSCs could
offer a new therapeutic approach. … and stem therapy to succeed in critical form of Covid-19. …