The interplay between inflammatory pathways and COVID-19: A critical review on pathogenesis and therapeutic options

S Choudhary, K Sharma, O Silakari - Microbial pathogenesis, 2021 - Elsevier
… These observations showed that targeting excessive host inflammation with a BTK
inhibitor is a therapeutic approach in severe COVID-19 and has resulted in a confirmatory …

Therapy for early COVID-19: a critical need

PS Kim, SW Read, AS Fauci - Jama, 2020 - jamanetwork.com
… early infection, this approach is also being explored for early, mild disease. Additionally,
approaches to prevent some of the more severe complications of COVID-19 are being tested. …

COVID-19: Advances in diagnostic tools, treatment strategies, and vaccine development

M Sreepadmanabh, AK Sahu, A Chande - Journal of biosciences, 2020 - Springer
… interest in the context of COVID-19 treatment approaches. While early … therapeutic agents
frequently associated with COVID-19 … Table 1 Leading therapeutic agents against COVID-19, …

COVID-19, an emerging coronavirus infection: advances and prospects in designing and developing vaccines, immunotherapeutics, and therapeutics

K Dhama, K Sharun, R Tiwari, M Dadar… - Human vaccines & …, 2020 - Taylor & Francis
… , the documented clinical data on different therapeutic approaches for CoVs are scarce.
Further research should be directed toward the study of SARS-CoV-2 in suitable animal models …

COVID-19: Pathogenesis, cytokine storm and therapeutic potential of interferons

SH Nile, A Nile, J Qiu, L Li, X Jia, G Kai - Cytokine & growth factor reviews, 2020 - Elsevier
… Recently, a number of specific anti-cytokine approaches have proven effective in the …
which, if any, of these therapeutics are effective in Covid-19-infected patients with cytokine storm …

[HTML][HTML] Dietary therapy and herbal medicine for COVID-19 prevention: A review and perspective

S Panyod, CT Ho, LY Sheen - Journal of traditional and complementary …, 2020 - Elsevier
… as the current allopathic therapy for COVID-19. Additionally, … of dietary therapy and herbal
medicine as COVID-19 preventive … 4 potential approaches for the application of dietary therapy

Immunobiology and immunotherapy of COVID19: A clinically updated overview

A Esmaeilzadeh, R Elahi - Journal of cellular physiology, 2021 - Wiley Online Library
… Here, we discuss different approaches to manage the cytokine storm in COVID-19. … In this
section, we describe different cell therapy methods developed for the treatment of COVID-19. …

Current pharmacological treatments for COVID19: What's next?

C Scavone, S Brusco, M Bertini… - British journal of …, 2020 - Wiley Online Library
… Lastly, given that the therapy for COVID-19 is dependent on the patients' immune system,
researchers are evaluating two possible engineering therapies, expanded umbilical cord …

A mechanistic model and therapeutic interventions for COVID-19 involving a RAS-mediated bradykinin storm

MR Garvin, C Alvarez, JI Miller, ET Prates, AM Walker… - elife, 2020 - elifesciences.org
… for COVID-19 are currently known. Here, we present a novel molecular mechanism for COVID-19
that provides therapeutic … lavage fluid (BALF) from COVID-19 patients that were used to …

JAK-STAT pathway inhibition and their implications in COVID-19 therapy

S Satarker, AA Tom, RA Shaji, A Alosious… - Postgraduate …, 2021 - Taylor & Francis
… Baricitinib is evident to be the safer approach in patients with moderate COVID-19 inhibiting
release of cytokines as an anti-inflammatory agent and endocytosis of SARS-CoV-2 virions […