… and it is also known to inhibit the OATP1B1-mediated hepatic uptake of substrates [49]. The
… of cyclosporine, as they are all the substrates of OATP1B1 transporter [50, 51]. Cyclosporine …

… drug-drug interactions (DDIs) has highlighted the clinical importance of hepatic organic
anion-transporting polypeptide transporters (OATPs), ABC drug … their broad substrate specificity …

… victim drugs due to OATP-mediated drug–drug interactions … of OATP1B1/1B3 and CYP3A4.
Moreover, most statins are not specifically transported by OATPs, but they are also substrates …

… a low potential for clinically relevant DDIs with drugs that are substrates for CYP or P-gp;
increased exposure of BCRP and probably OATP substrates was the main interaction of note. …

… Since several TKIs were previously determined to affect the function of OATPs, … drugs used
in various therapeutic areas that may cause drug-drug interactions with OATP2B1 substrates. …

… (OATP) 1B1/1B3-mediated drug-drug interactions (DDIs… OATP1B1/1B3 substrates are
anticipated to serve as surrogate probes to assess OATP1B1/1B3-mediated drug-drug interactions …

… drug interaction) in human and their clinical significances. … regarding clinical relevance are
OATP1B1 and OATP1B3 mainly … between OATP1B1 substrates and several OATP inhibitors. …

… As hypertension and diabetes are among the prevalent comorbidities in cancer patients,
many xenobiotic OATP1B1 and OATP1B3 substrate drugs are likely to be co-administrated with …

… include the following compounds: Rosuvastatin is a substrate for breast cancer resistance
protein (BCRP) and organic anion transporting polypeptides OATP1B1 and OATP1B3 (10, 93)…

… While the main focus of our review was P-gp induction, we also noted that the exposure
of pravastatin, an OATP substrate, was reduced by a similar extent as that for dabigatran …