… an embryonic HR capacity assay by exposing early stage embryos to ionizing radiation (90 …
Here we provide further evidence that a central node in the pathway is WRN’s regulation of …

… early studies suggest that they represent an important step forward in our ability to predict a
range of important age-… In summary, evidence is accumulating that DNAm plays a central role …

… epigenetic hallmarks of aging including evidence from preclinical … Studies of accelerated
aging syndromes or progerias … to address aging and age-related diseases is an early field but it …

… This review summarizes the current evidence pertaining to astrocyte senescence from
early evidence, in vitro characterization and relationship to age-related neurodegenerative …

… Accelerated aging is manifested by the earlier and faster development of the age-related
changes, which reduce the person’s life expectancy. It is known that physical activity has a …

… with biological aspects of aging. Data gathered from these early clocks can still be exploited
… be more powerful for accurate age prediction or to capture specific biological aging-related …

… muciniphila is associated with a healthy gut in early mid- and later life. However, the effects
of A. muciniphila on a … We now add evidence that A. muciniphila might protect against the …

… of accelerated aging across multiple biological metrics, including pubertal development and
cellular aging, … of adversity arguing that different forms of early-life adversity have unique …

… accelerate aging or if interventions may slow aging should not treat proposed measures of
aging … In a recent analysis of the Dunedin birth cohort at age 38 years, we found little evidence …

… We provide evidence that early targeting of senescent cells is therapeutic in moderating …
Recent studies have implicated mechanisms of accelerated aging, including loss of epithelial …