The emergence of COVID-19 as a global pandemic: Understanding the epidemiology, immune response and potential therapeutic targets of SARS-CoV-2

S Muralidar, SV Ambi, S Sekaran, UM Krishnan - Biochimie, 2020 - Elsevier
… , COVID-19 … , immune response, and therapeutic implications, possible drug targets, their
ongoing clinical trials, and put forward vital questions to offer new directions to the COVID-19

Immune-inflammatory parameters in COVID-19 cases: a systematic review and meta-analysis

X Feng, S Li, Q Sun, J Zhu, B Chen, M Xiong… - Frontiers in …, 2020 - frontiersin.org
… about inflammation and the immune response of patients with different severity of COVID-19
remains insufficient. Inflammation accompanied by an immune response often occurs in …

Avoiding pitfalls in the pursuit of a COVID-19 vaccine

L Peeples - Proceedings of the national academy of …, 2020 - National Acad Sciences
… A vaccine is designed to boost our natural immune response to an invading virus by priming
it to recognize antigens, unique molecules found on the surface of pathogens. Ideally, the …

[HTML][HTML] Detection of SARS-CoV-2-specific humoral and cellular immunity in COVID-19 convalescent individuals

L Ni, F Ye, ML Cheng, Y Feng, YQ Deng, H Zhao… - Immunity, 2020 - cell.com
… To understand immune responses to COVID-19, we assessed 14 patients who recently
recovered from the infection. Their clinical and pathological characteristics were shown in Table 1…

Rapid COVID-19 vaccine development

BS Graham - Science, 2020 - science.org
… (T H 1)–type immune response, which has … responses induced by protein-based vaccines
but can also influence T cell–derived cytokine patterns and thus modulate immune responses

Aging in COVID-19: Vulnerability, immunity and intervention

Y Chen, SL Klein, BT Garibaldi, H Li, C Wu… - Ageing research …, 2021 - Elsevier
… infections may induce heterotypic cellular immunity against COVID-19. This heterotypic
cellular immune response may further complicate COVID-19 immunological studies and …

[HTML][HTML] COVID-19-neutralizing antibodies predict disease severity and survival

WF Garcia-Beltran, EC Lam, MG Astudillo, D Yang… - Cell, 2021 - cell.com
… Taken together, our results highlight the impact of an effective humoral immune response
on COVID-19, as quantified by a neutralization potency index, and describe both the cytokines …

The clinical course and its correlated immune status in COVID-19 pneumonia

R He, Z Lu, L Zhang, T Fan, R Xiong, X Shen… - Journal of Clinical …, 2020 - Elsevier
… Severe SARS-CoV infected patients presented the delayed development of the adaptive
immune response and prolonged virus clearance 15 . SARS-CoV-2 may have the ability to …

Results of the RENAISSANCE Study: REsponse to BNT162b2 COVID-19 vacciNe—short-And long-term Immune reSponSe evAluatioN in health Care workErs

A Pani, V Cento, C Vismara, D Campisi… - Mayo Clinic …, 2021 - Elsevier
… the serologic response to the BNT162b2 COVID-19 vaccine in the staff of the main COVID-19
COVID-19 at day 14 after the second vaccine dose in more than 2500 health care workers. …

[PDF][PDF] Coronavirus COV-19/SARS-CoV-2 affects women less than men: clinical response to viral infection

P Conti, A Younes - J Biol Regul Homeost Agents, 2020 - researchgate.net
19/SARS-CoV-2 is a highly pathogenic virus that causes coronavirus-19 disease (COVID-19
men and women in the immune response to CoV-19 infection and inflammatory diseases. …