… cytokines in COVID-19 patients: A review on molecular mechanisms, immune functions, immunopathology and immunomodulatory drugs to counter cytokine storm

AA Rabaan, SH Al-Ahmed, J Muhammad, A Khan… - Vaccines, 2021 - mdpi.com
… to shed light on the molecular mechanisms of the cytokines and their functions and impact
on the pathology of COVID-19. Furthermore, the immunomodulatory therapeutic strategies are …

Novel immunomodulatory drugs and neo-substrates

S Gao, S Wang, Y Song - Biomarker Research, 2020 - Springer
… lenalidomide and pomalidomide, are called immunomodulatory drugs (IMiDs). In addition, …
several hematological malignancies, the molecular mechanism remained unclear at that time. …

Infectious complications of biological and small molecule targeted immunomodulatory therapies

JS Davis, D Ferreira, E Paige, C Gedye… - Clinical microbiology …, 2020 - Am Soc Microbiol
… For each of 19 classes of agent, we discuss the mechanism of action, the risk and types of …
agent or small molecule in one review article, and there are several groups of drugs we have …

[HTML][HTML] Developing next generation immunomodulatory drugs and their combinations in multiple myeloma

A Thakurta, WE Pierceall, MD Amatangelo, E Flynt… - Oncotarget, 2021 - ncbi.nlm.nih.gov
mechanisms. Based on the types of combinations used and the goals of therapy, insights
into mechanisms of drug … of the molecular mechanisms of CRBN-binding drugs and how they …

Folic acid antagonists: antimicrobial and immunomodulating mechanisms and applications

D Fernández-Villa, MR Aguilar, L Rojo - International journal of molecular …, 2019 - mdpi.com
… While its antibacterial mechanism of action is well-stablished (inhibiting bacterial DHPS like
most sulfonamides), there is no data analyzing the molecular mechanism underlying its anti-…

Mesenchymal stem cell immunomodulation: mechanisms and therapeutic potential

N Song, M Scholtemeijer, K Shah - Trends in pharmacological sciences, 2020 - cell.com
… Previous studies have confirmed that the immunomodulatoryimmunomodulatory potential,
in which regulatory T cells and monocytes play a key role. We review the immunomodulatory

Pharmaco-immunomodulatory therapy in COVID-19

JG Rizk, K Kalantar-Zadeh, MR Mehra, CJ Lavie… - Drugs, 2020 - Springer
… Thus, tackling the immune response with immunomodulatory agents may … immunomodulating
agents, including neutralizing monoclonal antibodies, corticosteroids, and other molecules

Sulfated polysaccharides: Immunomodulation and signaling mechanisms

L Huang, M Shen, GA Morris, J Xie - Trends in Food Science & Technology, 2019 - Elsevier
… With the advancements in molecular biology, genomics, proteomics, and molecular
nutrition, the structure-activity relationship and molecular mechanisms involved in the immune …

Immunomodulation by mesenchymal stem cells (MSCs): mechanisms of action of living, apoptotic, and dead MSCs

ARR Weiss, MH Dahlke - Frontiers in immunology, 2019 - frontiersin.org
… have similar immunomodulatory capacities remains elusive. Here we review the current …
on cellular and molecular mechanisms involved in MSC-mediated immunomodulation and …

[HTML][HTML] A review on the pharmacokinetics of paeoniflorin and its anti-inflammatory and immunomodulatory effects

YX Zhou, XH Gong, H Zhang, C Peng - Biomedicine & Pharmacotherapy, 2020 - Elsevier
… However, further studies are needed to clarity the direct molecular mechanisms and key
targets underlying the beneficial effects of paeoniflorin on inflammation and immunity. …