Multidrug resistance in cancer: understanding molecular mechanisms, immunoprevention and therapeutic approaches

TB Emran, A Shahriar, AR Mahmud, T Rahman… - Frontiers in …, 2022 - frontiersin.org
… Understanding the molecular mechanisms that result in the development of drug resistance
is an increasingly important issue, which has been approached through the comprehensive …

Mesenchymal stem cells immunomodulation: The road to IFN-γ licensing and the path ahead

AÉ Silva-Carvalho, MRR Sousa, T Alencar-Silva… - Cytokine & growth factor …, 2019 - Elsevier
immunomodulatory function, as well as the mixed results published so far, we will discuss, in
the present review: the main mechanisms … to elucidate the molecular mechanisms used by …

Potential therapeutic anti-inflammatory and immunomodulatory effects of dihydroflavones, flavones, and flavonols

C Zaragozá, L Villaescusa, J Monserrat, F Zaragozá… - Molecules, 2020 - mdpi.com
… Control of the molecular and cellular mechanisms involved in these processes is an area
of intense research. Some flavonoids have shown the ability to inhibit platelet activation and …

Immunomodulatory effects of edible and medicinal mushrooms and their bioactive immunoregulatory products

S Zhao, Q Gao, C Rong, S Wang, Z Zhao, Y Liu, J Xu - Journal of Fungi, 2020 - mdpi.com
… We then summarize the diversity, structure, function, and molecular mechanism of action
of functional ingredients from MMs that have shown to be involved in immunomodulation. We …

Curcumin and intestinal inflammatory diseases: molecular mechanisms of protection

K Burge, A Gunasekaran, J Eckert… - … journal of molecular …, 2019 - mdpi.com
… In this review, we explore the potential therapeutic properties of curcumin on intestinal
inflammatory diseases, including its antimicrobial and immunomodulatory properties, as well as …

Molecular basis and rationale for combining immune checkpoint inhibitors with chemotherapy in non-small cell lung cancer

A Leonetti, B Wever, G Mazzaschi, YG Assaraf… - Drug Resistance …, 2019 - Elsevier
… Taking into account the multiple mechanisms adopted by … the molecular mechanisms
underlying immunomodulation by … and anthracyclines), unraveling drug- and dose/schedule-…

Immunomodulatory effects of flavonoids: possible induction of T CD4+ regulatory cells through suppression of mTOR pathway signaling activity

A Hosseinzade, O Sadeghi… - Frontiers in …, 2019 - frontiersin.org
… Flavonoids are able to modulate immune response, though the exact molecular
mechanisms involved in these changes are not well understood. Flavonoids also have anti-proliferative …

A review: Mechanism of action of antiviral drugs

S Kausar, F Said Khan… - International journal …, 2021 - journals.sagepub.com
… In recent years, there has been tremendous progress in understanding the genetic basis
and molecular mechanism of diseases. Various new drugs have been formulated and the …

Immunomodulation by inflammation during liver and gastrointestinal tumorigenesis and aging

N Nagai, Y Kudo, D Aki, H Nakagawa… - … journal of molecular …, 2021 - mdpi.com
Chronic inflammation is thought to promote tumorigenesis and metastasis by several
mechanisms, such as affecting tumor cells directly, establishing a tumor-supporting …

Immunomodulatory and anti-inflammatory effects of fucoidan: A review

E Apostolova, P Lukova, A Baldzhieva, P Katsarov… - Polymers, 2020 - mdpi.com
… their anti-inflammatory and immunomodulatory mechanisms of action. Undaria pinnatifida
… influence the anti-inflammatory and immunomodulatory activity of fucoidan. Menshova et al. […