Immunology, immunopathogenesis and immunotherapeutics of COVID-19; an overview

LM Khosroshahi, M Rokni, T Mokhtari… - International …, 2021 - Elsevier
… -19 is important in developing effective therapies as well as … disease-associated cytokine
storm syndrome may have mutations … of COVID-19 associated cytokine storm syndrome may, to …

The bio-mission of interleukin-6 in the pathogenesis of COVID-19: A brief look at potential therapeutic tactics

M Abbasifard, H Khorramdelazad - Life sciences, 2020 - Elsevier
cytokine storm can also cause MOF and ultimately lead to death. Therefore, understanding
the precise role of inflammatory cytokines such as IL-6 is crucial in the immunopathogenesis

Tackling the cytokine storm in COVID-19, challenges and hopes

SM Abdin, SM Elgendy, SK Alyammahi, DW Alhamad… - Life Sciences, 2020 - Elsevier
… In this review, we provide a detailed insight into the cytokine storm phenomena as one of …
the potential therapeutic agents that could block or interfere with the cytokine storm, and …

[HTML][HTML] Prospects and opinions in immunopathogenesis of COVID-19

FHO Al-Khikani - Matrix Science Medica, 2021 - journals.lww.com
… immune reaction in the host that called a cytokine storm, the effect is extensive tissue
destruction. This storm is protagonized by IL-6. It is produced by activated leukocytes and also acts …

[HTML][HTML] Cytokine storm in novel coronavirus disease (COVID-19): expert management considerations

Y Mehta, SB Dixit, KG Zirpe… - Indian journal of critical …, 2020 - ncbi.nlm.nih.gov
… This immunopathogenesis leads to acute lung injury and acute respiratory distress syndrome
(ARDS). Targeting cytokine storm with the therapies that are already available in India with …

[HTML][HTML] IMMUNOPATHOGENETIC BASES OF SEVERITY OF COVID-19. LITERATURE REVIEW

AA Yessenbayeva, MS Kazymov… - Наука и …, 2022 - cyberleninka.ru
… COVID-19 and its immunopathogenetic basis for the severity of the … There is clinical evidence
that suggests that cytokine storm is … of pro - inflammatory cytokines - a cytokine storm that is …

[HTML][HTML] Therapeutic role of tocilizumab in SARS-CoV-2-induced cytokine storm: rationale and current evidence

C Pelaia, C Calabrese, E Garofalo, A Bruni… - International Journal of …, 2021 - mdpi.com
… COVID-19-associated cytokine storm. In this regard, the IL-6 receptor antagonist tocilizumab,
… article aims to discuss the immunopathology of the cytokine storm caused by SARS-CoV-2 …

[HTML][HTML] Severe COVID-19: what have we learned with the immunopathogenesis?

B Bordallo, M Bellas, AF Cortez, M Vieira… - Advances in …, 2020 - SciELO Brasil
… response, lymphocyte exhaustion and cytokine storm that ultimately lead to … therapeutic
strategies. In this narrative review, the authors aimed to describe the immunopathogenesis of …

Cytokine storm in COVID-19 and other diseases: emerging therapeutic interventions

S Sahu, R Dharra, M Gun, S Datta, AK Akela, A Kumar - Stem Cells, 2024 - Elsevier
… In CS, the immune system produces elevated proinflammatory cytokines’ … cytokines that
result in the abnormal immune response by the host. This chapter includes different therapeutic

[HTML][HTML] Current concepts on immunopathology of COVID-19 and emerging therapies

L Azimi, A Karimi, M Alebouyeh, A Shirvani… - Archives of Pediatric …, 2020 - brieflands.com
… on the immunopathogenicity of SARS-… cytokine storm and inflammation, and diminished T
lymphocytes count were reported as possible mechanisms for the virus immunopathogenesis. …