Dapk1 improves inflammation, oxidative stress and autophagy in LPS-induced acute lung injury via p38MAPK/NF-κB signaling pathway

T Li, YN Wu, H Wang, JY Ma, SS Zhai, J Duan - Molecular immunology, 2020 - Elsevier
… by sepsis is lung, with development of acute lung injury (ALI), … Also, the mortality rate of
sepsis-induced lung injury is still … The pathogenesis of sepsis-induced lung injury has not been …

[HTML][HTML] Oridonin protects LPS-induced acute lung injury by modulating Nrf2-mediated oxidative stress and Nrf2-independent NLRP3 and NF-κB pathways

H Yang, H Lv, H Li, X Ci, L Peng - Cell Communication and Signaling, 2019 - Springer
… Furthermore, it was proven to relieve acute lung injury and vascular inflammation by … on the
oxidative stress and inflammation generated from LPS-induced acute lung injury. Additionally…

[HTML][HTML] Oxidative stress-induced FABP5 S-glutathionylation protects against acute lung injury by suppressing inflammation in macrophages

Y Guo, Y Liu, S Zhao, W Xu, Y Li, P Zhao… - Nature …, 2021 - nature.com
… We next explored which type of cell is more sensitive to oxidative stress during the
pathogenesis of acute lung injury. First, the intracellular ROS level was monitored using 2′, 7′-…

Polysaccharides from Dendrobium officinale ameliorate colitis-induced lung injury via inhibiting inflammation and oxidative stress

Y Wen, H Xiao, Y Liu, Y Yang, Y Wang, S Xu… - Chemico-Biological …, 2021 - Elsevier
… factor Nrf2 in lung is blocked and … oxidative injury in the lung [22]. In addition, many evidences
have confirmed that Nrf2, as a sensor of oxidative stress, plays protective role in lung injury

Baicalin ameliorates lipopolysaccharide-induced acute lung injury in mice by suppressing oxidative stress and inflammation via the activation of the Nrf2-mediated HO …

X Meng, L Hu, W Li - Naunyn-Schmiedeberg's Archives of Pharmacology, 2019 - Springer
… acute lung injury by the suppression of oxidative stress and … -induced acute lung injury is
based on its antioxidative stress … decreased the rise in the lung injury score; total leukocyte, …

[HTML][HTML] … activates the p62–Keap1–Nrf2 signalling pathway to alleviate oxidative stress and excessive autophagy in severe acute pancreatitis-related acute lung injury

L Kong, J Deng, X Zhou, B Cai, B Zhang, X Chen… - Cell death & …, 2021 - nature.com
Acute lung injury (ALI) is a complication of severe acute pancreatitis (SAP). Sitagliptin (SIT)
is a DPP4 inhibitor that exerts anti-inflammatory and antioxidant effects; however, its …

Oxidative stress promotes ventilator-induced lung injury through activating NLRP3 inflammasome and TRPM2 channel

X An, X Sun, X Yang, D Liu, Y Hou… - Artificial cells …, 2019 - Taylor & Francis
Oxidative stress has been believed to be a contributor to VILI… the influence of oxidative stress
on NLRP3 inflammasome, … that oxidative stress may influence ventilator-induced lung injury

S-allylmercaptocysteine ameliorates lipopolysaccharide-induced acute lung injury in mice by inhibiting inflammation and oxidative stress via nuclear factor kappa B …

M Mo, S Li, Z Dong, C Li, Y Sun, A Li, Z Zhao - International …, 2020 - Elsevier
… Acute lung injury (ALI) and its more severe manifestation, acute respiratory … to lung can
not only markedly trigger pulmonary inflammation but also apparently prompt oxidative stress, …

[HTML][HTML] Mucin1 relieves acute lung injury by inhibiting inflammation and oxidative stress

C Ye, B Xu, J Yang, Y Liu, Z Zeng, L Xia… - European Journal of …, 2021 - ncbi.nlm.nih.gov
… reduces oxidative stress level in mouse lung tissue To further investigate the protective
effect of MUC1 on the lung, we examined the effect of MUC1 on oxidative stress in lung tissue. …

[HTML][HTML] … injury by hispolon in mice, through regulating the TLR4/PI3K/Akt/mTOR and Keap1/Nrf2/HO-1 pathways, and suppressing oxidative stress-mediated ER stress …

CY Huang, JS Deng, WC Huang, WP Jiang, GJ Huang - Nutrients, 2020 - mdpi.com
… against infection, these stress markers ultimately release … the oxidative stress marker
antioxidant enzymes and MPO. Surprisingly, hispolon significantly improved the oxidative stress