… , given that MERS coronavirus appears to … MERS coronavirus, 3, 4 and WHO has developed
a target product profile for both preventive and reactive use of MERS coronavirus vaccines. …

… vaccine has not been developed for it. To develop a vaccine against multiple strains of
MERS-CoV, we targeted spike glycoprotein (S) using prime-boost vaccination with DNA and …

… Here, we illustrate the importance of the MERS-CoV S protein as a key vaccine target and
… MERS-CoV DNA vaccines utilize different vectors to encode the full-length MERS-CoV S …

… highlight the urgent development of vaccines. Among the technologies available for vaccine
development, DNA vaccination is a promising alternative to conventional vaccines. Since its …

… the GLS-5300 MERS coronavirus DNA vaccine was tolerable and immunogenic in humans.
The vaccine induced both antibody-based and cellular MERS coronavirus-specific immune …

… neutralize SARS-CoV and MERS-CoV and provides protective … -based vaccines against
SARS-CoV and MERS-CoV have … subunit vaccines, virus-like particle vaccines, DNA vaccines, …

… coronavirus (MERS-CoV) can initiate vaccine production faster for Severe Acute Respiratory
Syndrome Coronavirus 2 (SARS-CoV-2)… DNA sequencing of SARS-CoV-2 with MERS-CoV …

… target for development of MERS vaccines and therapeutics. In this … the MERS-CoV S-protein
RBD, summarize recent advances in the development of MERS-CoV RBD-based vaccines …

… cannot be excluded for vaccines containing viral DNA, and also those based on RNA. In this
… could lead to DNA production theoretically starting also from the vaccine-delivered RNAs. …

… Another study demonstrated that mice vaccinated with DNA encoding the modified SARS-CoV-S
glycoprotein developed protective immunity resulting from the induction of T cells and …