… virus (ZIKV) emerged in northeast Brazil in 2015 and spread rapidly across the Americas, in
populations that have been largely exposed to dengue virus (… in Managua, Nicaragua, in a …

… We analyzed virus consensus genomes from Nicaragua in a phylogenetic context that
included publicly available complete-genome sequences from Central and South America and …

… a cohort of 5,940 Nicaraguan children followed over 9 years. Children with obesity were
more likely to be infected with dengue virus and had higher risk of developing dengue disease. …

… Our phylogenetic analyses confirmed that all Nicaraguan DENV-2 isolates from 2018 to
2019 formed their own clade within the Nicaraguan lineage of the Asian/American genotype. …

… We analyzed dengue virus (DENV) disease severity stratified by serotype and immune
status over 19 years of two pediatric studies in Nicaragua. DENV2 and DENV3 caused the most …

… Our study, spanning 17 years of prospective cohort data in Nicaragua, addresses this
bottleneck in dengue research by providing a detailed examination of primary inapparent infections…

… An additional challenge is that ZIKV often circulates alongside other arboviruses, such as
dengue virus (DENV), which is another flavivirus, and chikungunya virus. These …

… In our study, as well as the study of a pediatric cohort in Nicaragua, the results suggested
that the duration of cross-immunity is approximately 2 years and is associated with non-severe …

… creates an increased risk for severe dengue virus sereotype 2 infection. By contrast, … We
investigated prospective pediatric cohorts in Nicaragua that experienced sequential DENV1 to -…

… dengue epidemics throughout Nicaragua’s history have been dominated by 1 of 4 dengue
virus … To examine serotypes during the dengue epidemic in Nicaragua in 2022, we performed …