SI Hirai, RP Ryseck, F Mechta, R Bravo… - The EMBO journal, 1989 - embopress.org
In an extensive screen of a cDNA library prepared from serum‐stimulated mouse NIH 3T3 cells, we identified three distinct jun‐related clones. Two of them were carrying c‐jun and …
AG Hinnebusch - Molecular and cellular biology, 1985 - Taylor & Francis
The GCN4 gene encodes a positive effector of amino acid biosynthetic genes in Saccharomyces cerevisiae. Genetic analysis has suggested that GCN4 is regulated by a …
TJ Bos, D Bohmann, H Tsuchie, R Tijan, PK Vogt - Cell, 1988 - Elsevier
The jun oncogene of ASV17 is expressed as a 65 kd protein (p65 gag-jun) that contains partial gag sequences at its amino terminus fused to jun sequences that make up the …
The AP-1 transcriptional activating complex, made up of Jun and Fos protein, is involved in controlling many cellular processes such as cell proliferation, differentiation and …
Yeast GCN4 protein binds specifically to the promoters of amino acid biosynthetic genes and coordinately induces their transcription. Serially deleted GCN4 and hybrid LexA-GCN4 …
DM Benbrook, NC Jones - Oncogene, 1990 - ouhsc.edu
DNA binding protein families have been identified that contain a leucine zipper dimerization motif preceded by a conserved, highly basic domain involved in direct specific interaction …
T Deng, M Karin - Genes & development, 1993 - genesdev.cshlp.org
JunB differs considerably from c-Jun in its ability to activate AP-1-responsive genes and induce oncogenic transformation. We demonstrate that the decreased ability of JunB to …
J Schütte, JD Minna, MJ Birrer - Proceedings of the …, 1989 - National Acad Sciences
While the ability of the retroviral oncogene V-jun to transform chicken cells led to its discovery, the oncogenic potential of its cellular homologue, c-jun, which encodes a …
Abstract A STRUCTURAL motif for DNA-binding proteins, the" leucine zipper", has been proposed for the jun, fos and myc gene products, the yeast transcriptional activator GCN4 …