Activation of junB by PKC and PKA signal transduction through a novel cis-acting element

RP de Groot, J Auwerx, M Karperien… - Nucleic acids …, 1991 - academic.oup.com
The product of the junB gene, a gene homologous to the proto-oncogene c-jun, is a
component of transcription factor AP-1. JunB expression is modulated by a wide variety of …

Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity

WJ Boyle, T Smeal, LHK Defize, P Angel, JR Woodgett… - Cell, 1991 - cell.com
In resting human epithelial and fibroblastic cells, c-Jun is phosphorylated on serine and
threonine at five sites, three of which are phosphorylated in vitro by glycogen synthase …

Developmental expression of genes involved in conidiation and amino acid biosynthesis in Neurospora crassa

MS Sachs, C Yanofsky - Developmental biology, 1991 - Elsevier
The levels of transcripts for Neurospora crassa genes concerned with cellular and metabolic
functions changed dramatically at different stages of asexual development. Transcripts for …

Structure and Expression of the Rat c-jun Messenger RNA: Tissue Distribution and Increase during Chemical Hepatocarcinogenesis

M Sakai, A Okuda, I Hatayama, K Sato, S Nishi… - Cancer research, 1989 - AACR
Abstract c-jun is the cellular homologue of the recently isolated nuclear oncogene v-jun. This
protooncogene encodes the cellular transcription factor AP-1. We have isolated the …

Multiple GCD genes required for repression of GCN4, a transcriptional activator of amino acid biosynthetic genes in Saccharomyces cerevisiae

S Harashima, AG Hinnebusch - Molecular and cellular biology, 1986 - Am Soc Microbiol
GCN4 encodes a positive regulator of multiple unlinked genes encoding amino acid
biosynthetic enzymes in Saccharomyces cerevisiae. Expression of GCN4 is coupled to …

In vivo protein-DNA interactions at the c-jun promoter: preformed complexes mediate the UV response

D Rozek, GP Pfeifer - Molecular and cellular biology, 1993 - Am Soc Microbiol
Irradiation of cells with UV light triggers a genetic response, called the UV response, which
results in induction of a set of genes containing AP-1-binding sites. The c-jun gene itself …

A yeast transcriptional stimulatory protein similar to human PC4

NL Henry, DA Bushnell, RD Kornberg - Journal of Biological Chemistry, 1996 - ASBMB
A yeast protein has been identified that stimulates basal transcription by RNA polymerase II,
binds both single-and double-stranded DNA, and interacts with both a general transcription …

Characterization of rco-1 of Neurospora crassa, a pleiotropic gene affecting growth and development that encodes a homolog of Tup1 of Saccharomyces cerevisiae

CT Yamashiro, DJ Ebbole, BU Lee… - … and cellular biology, 1996 - Taylor & Francis
The filamentous fungus Neurospora crassa undergoes a well-defined developmental
program, conidiation, that culminates in the production of numerous asexual spores, conidia …

Identification of domains of c-Jun mediating androgen receptor transactivation

SC Wise, LA Burmeister, X Zhou, A Bubulya… - Oncogene, 1998 - nature.com
The proto-oncoprotein c-Jun, when complexed with c-Fos, forms the climeric complex
identified as AP-1 which regulates transcription directly by binding to AP-1-responsive …

Transformation by Raf and other oncogenes renders cells differentially sensitive to growth inhibition by a dominant negative c-jun mutant.

UR Rapp, J Troppmair, T Beck, MJ Birrer - Oncogene, 1994 - europepmc.org
In NIH3T3 cells expressing active Raf-1 protein serine/threonine kinase (PSK) c-jun
expression is constitutive while c-fos expression is attenuated. This alteration prompted us to …