Bicuspid aortic valve: phosphorylation of c-Kit and downstream targets are prognostic for future aortopathy

N Grewal, AC Gittenberger-de Groot… - European Journal of …, 2014 - academic.oup.com
OBJECTIVES The clinical course of many patients with a bicuspid aortic valve (BAV) is
complicated by ascending aortic dilatation. Currently, the indication for aortic surgery is …

[HTML][HTML] Should the proximal arch be routinely replaced in patients with bicuspid aortic valve disease and ascending aortic aneurysm?

CB Park, KL Greason, RM Suri, HI Michelena… - The Journal of Thoracic …, 2011 - Elsevier
OBJECTIVES: Bicuspid aortic valve is frequently associated with underlying aortopathy.
Data support an aggressive approach to replacement of the ascending aorta. However, the …

Predictors of ascending aorta enlargement and valvular dysfunction progression in patients with bicuspid aortic valve

A Lopez, I Dentamaro, L Galian, F Calvo… - Journal of Clinical …, 2021 - mdpi.com
Bicuspid aortic valve (BAV) patients are at high risk of developing progressive aortic valve
dysfunction and ascending aorta dilation. However, the progression of the disease is not …

Replacement of the ascending aorta in bicuspid aortic valve disease: where do we draw the line?

TM Sundt - The Journal of Thoracic and Cardiovascular Surgery, 2010 - jtcvs.org
During the past decade, there has been increasing attention to the risk of aortic
complications associated with bicuspid aortic valve (BAV) disease. BAV is a curious …

Transcatheter aortic valve replacement in bicuspid aortic valve stenosis: where do we stand?

SH Yoon, R Sharma, T Chakravarty… - The Journal of …, 2018 - europepmc.org
Bicuspid aortic valve is the most common congenital cardiac defect in adults, and symptom
typically develops in adulthood. In the majority of cases, bicuspid aortic valve disease …

[HTML][HTML] Should the ascending aorta be replaced more frequently in patients with bicuspid aortic valve disease?

MA Borger, M Preston, J Ivanov, PWM Fedak… - The Journal of thoracic …, 2004 - Elsevier
OBJECTIVE: The optimal diameter at which replacement of the ascending aorta should be
performed in patients with bicuspid aortic valve disease is not known. METHODS: We …

Does the leaflet fusion subtype affect pattern and rate of growth in BAV aortopathy?: A study of 102 BAV aortopathy cases with a literature review

A Hardikar, R Harle - Heart, Lung and Circulation, 2021 - Elsevier
Background Bicuspid aortic valves (BAV) and related aortopathy remain an intriguing topic.
Not all BAVs get diseased and around 40% would develop aortic dilatation in their lifetime. If …

Retrospective study to identify predictors of the presence and rapid progression of aortic dilatation in patients with bicuspid aortic valves

G Thanassoulis, JWL Yip, K Filion, M Jamorski… - Nature clinical practice …, 2008 - nature.com
Background Aortic dilatation is common among adults with bicuspid aortic valves (BAV).
Predictors of risk and progression of aortic dilatation are not well described in this setting …

The influence of operative techniques on the outcomes of bicuspid aortic valve disease and aortic dilatation

RI Nazer, AM Elhenawy, SS Fazel… - The Annals of thoracic …, 2010 - Elsevier
BACKGROUND: Bicuspid aortic valve is associated with aortic aneurysm formation that may
extend beyond the ascending aorta. METHODS: Between 1979 and 1997, 143 bicuspid …

Bicuspid aortic valve disease and ascending aortic aneurysm: should an aortic root replacement be mandatory?

I Vendramin, M Meneguzzi, S Sponga… - European Journal of …, 2016 - academic.oup.com
OBJECTIVES The higher risk of adverse aortic events in patients with bicuspid aortic valve
(BAV) disease and ascending aorta aneurysm is known, but the management of moderate …