Divergent SARS‐CoV‐2‐specific T‐and B‐cell responses in severe but not mild COVID‐19 patients

AE Oja, A Saris, CA Ghandour… - European journal of …, 2020 - Wiley Online Library
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is the causative agent of
the current coronavirus disease 2019 (COVID‐19) pandemic. Understanding the immune …

[HTML][HTML] Impaired cellular immunity to SARS-CoV-2 in severe COVID-19 patients

L Ni, ML Cheng, Y Feng, H Zhao, J Liu, F Ye… - Frontiers in …, 2021 - frontiersin.org
The high infection rate and rapid spread of severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) make it a world-wide pandemic. Individuals infected by the virus exhibited …

Immunological imprint of COVID‐19 on human peripheral blood leukocyte populations

B Kratzer, D Trapin, P Ettel, U Körmöczi, A Rottal… - Allergy, 2021 - Wiley Online Library
Background SARS‐CoV‐2 has triggered a pandemic that is now claiming many lives.
Several studies have investigated cellular immune responses in COVID‐19‐infected …

Decline in neutralising antibody responses, but sustained T‐cell immunity, in COVID‐19 patients at 7 months post‐infection

J Chen, X Liu, X Zhang, Y Lin, D Liu… - Clinical & …, 2021 - Wiley Online Library
Objectives This study aimed to explore the severe acute respiratory syndrome coronavirus 2
(SARS‐CoV‐2)‐specific humoral responses and T‐cell responses in patients who have …

[HTML][HTML] Pro-and anti-inflammatory responses in severe COVID-19-induced acute respiratory distress syndrome—an observational pilot study

Q Notz, M Schmalzing, F Wedekink… - Frontiers in …, 2020 - frontiersin.org
Objectives The severity of Coronavirus Disease 2019 (COVID-19) is largely determined by
the immune response. First studies indicate altered lymphocyte counts and function …

Phenotype and kinetics of SARS-CoV-2–specific T cells in COVID-19 patients with acute respiratory distress syndrome

D Weiskopf, KS Schmitz, MP Raadsen, A Grifoni… - Science …, 2020 - science.org
SARS-CoV-2 has been identified as the causative agent of a global outbreak of respiratory
tract disease (COVID-19). In some patients, the infection results in moderate to severe acute …

SARS‐CoV‐2‐specific humoral and cellular immunity persists through 9 months irrespective of COVID‐19 severity at hospitalisation

JT Sandberg, R Varnaitė, W Christ… - Clinical & …, 2021 - Wiley Online Library
Objectives Humoral and cellular immunity to SARS‐CoV‐2 following COVID‐19 will likely
contribute to protection from reinfection or severe disease. It is therefore important to …

[HTML][HTML] Dynamics of CD4 T cell and antibody responses in COVID-19 patients with different disease severity

M Koblischke, MT Traugott, I Medits, FS Spitzer… - Frontiers in …, 2020 - frontiersin.org
Disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
ranges from mild illness to severe respiratory disease and death. In this study, we …

The T-cell response to SARS-CoV-2: kinetic and quantitative aspects and the case for their protective role

A Bertoletti, AT Tan, N Le Bert - Oxford Open Immunology, 2021 - academic.oup.com
Abstract Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2), the etiological
agent of Coronavirus Diseases 2019 (COVID-19), triggers an adaptive immunity in the …

[HTML][HTML] Long-term SARS-CoV-2-specific immune and inflammatory responses in individuals recovering from COVID-19 with and without post-acute symptoms

MJ Peluso, AN Deitchman, L Torres, NS Iyer… - Cell Reports, 2021 - cell.com
We describe severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific T cell
responses, soluble markers of inflammation, and antibody levels and neutralization capacity …