Presence of SARS-CoV-2-reactive T cells in COVID-19 patients and healthy donors

J Braun, L Loyal, M Frentsch, D Wendisch, P Georg… - MedRxiv, 2020 - medrxiv.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a rapidly
unfolding pandemic, overwhelming health care systems worldwide 1. Clinical manifestations …

SARS-CoV-2 infection results in immune responses in the respiratory tract and peripheral blood that suggest mechanisms of disease severity

W Zhang, BY Chua, KJ Selva, L Kedzierski… - Nature …, 2022 - nature.com
Respiratory tract infection with SARS-CoV-2 results in varying immunopathology underlying
COVID-19. We examine cellular, humoral and cytokine responses covering 382 immune …

Single-cell immune profiling reveals distinct immune response in asymptomatic COVID-19 patients

XN Zhao, Y You, XM Cui, HX Gao, GL Wang… - Signal transduction and …, 2021 - nature.com
While some individuals infected by severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) present mild-to-severe disease, many SARS-CoV-2-infected individuals are …

[HTML][HTML] The immune response to SARS-CoV-2 and COVID-19 immunopathology–Current perspectives

JL Boechat, I Chora, A Morais, L Delgado - Pulmonology, 2021 - Elsevier
SARS-CoV-2 is a new beta coronavirus, similar to SARS-CoV-1, that emerged at the end of
2019 in the Hubei province of China. It is responsible for coronavirus disease 2019 (COVID …

Immunological and inflammatory profiles in mild and severe cases of COVID-19

JW Song, C Zhang, X Fan, FP Meng, Z Xu, P Xia… - Nature …, 2020 - nature.com
Abstract COVID-19 is associated with 5.1% mortality. Although the virological,
epidemiological, clinical, and management outcome features of COVID-19 patients have …

Unraveling the mystery surrounding post-acute sequelae of COVID-19

RK Ramakrishnan, T Kashour, Q Hamid… - Frontiers in …, 2021 - frontiersin.org
More than one year since its emergence, corona virus disease 2019 (COVID-19) is still
looming large with a paucity of treatment options. To add to this burden, a sizeable subset of …

[HTML][HTML] The potential clinical utility of measuring severe acute respiratory syndrome coronavirus 2-specific T-cell responses

D Goletti, L Petrone, D Manissero, A Bertoletti… - Clinical Microbiology …, 2021 - Elsevier
Background Both humoral and cell-mediated responses are associated with immunity to
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Although our …

[HTML][HTML] COVID-19 immune signatures reveal stable antiviral T cell function despite declining humoral responses

A Bonifacius, S Tischer-Zimmermann, AC Dragon… - Immunity, 2021 - cell.com
Cellular and humoral immunity to SARS-CoV-2 is critical to control primary infection and
correlates with severity of disease. The role of SARS-CoV-2-specific T cell immunity, its …

The deciphering of the immune cells and marker signature in COVID‐19 pathogenesis: An update

SA Jasim, RS Mahdi, DO Bokov… - Journal of Medical …, 2022 - Wiley Online Library
The precise interaction between the immune system and severe acute respiratory syndrome
coronavirus 2 (SARS‑CoV‑2) is critical in deciphering the pathogenesis of coronavirus …

Dysregulation of the immune response in coronavirus disease 2019

L Mohamed Khosroshahi, N Rezaei - Cell Biology International, 2021 - Wiley Online Library
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) can trigger a cytokine
storm in the pulmonary tissue by releasing various types of mediators, leading to acute …