[HTML][HTML] Immunology of COVID-19: current state of the science

N Vabret, GJ Britton, C Gruber, S Hegde, J Kim… - Immunity, 2020 - cell.com
The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has affected millions of people worldwide, igniting …

T cell activation, highly armed cytotoxic cells and a shift in monocytes CD300 receptors expression is characteristic of patients with severe COVID-19

O Zenarruzabeitia, G Astarloa-Pando, I Terren… - Frontiers in …, 2021 - frontiersin.org
COVID-19 manifests with a wide diversity of clinical phenotypes characterized by
dysfunctional and exaggerated host immune responses. Many results have been described …

[HTML][HTML] Expansion of SARS-CoV-2–specific antibody-secreting cells and generation of neutralizing antibodies in hospitalized COVID-19 patients

R Varnaitė, M García, H Glans, KT Maleki… - The Journal of …, 2020 - journals.aai.org
Abstract Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), emerged in late 2019 and has since become a …

Impaired immune cell cytotoxicity in severe COVID-19 is IL-6 dependent

A Mazzoni, L Salvati, L Maggi… - The Journal of …, 2020 - Am Soc Clin Investig
BACKGROUND Coronavirus disease 19 (COVID-19) is an emerging infectious disease
caused by SARS-CoV-2. Antiviral immune response is crucial to achieve pathogen …

[HTML][HTML] SARS-CoV-2 specific T-cell immunity in COVID-19 convalescent patients and unexposed controls measured by ex vivo ELISpot assay

I Cassaniti, E Percivalle, F Bergami, A Piralla… - Clinical Microbiology …, 2021 - Elsevier
Abstract Objectives SARS-CoV-2 T-cell response characterization represents a crucial issue
for defining the role of immune protection against COVID-19. The aim of the study was to …

Monocytes and macrophages, targets of severe acute respiratory syndrome coronavirus 2: the clue for coronavirus disease 2019 immunoparalysis

A Boumaza, L Gay, S Mezouar, E Bestion… - The Journal of …, 2021 - academic.oup.com
Abstract Background Coronavirus disease 2019 (COVID-19) clinical expression is
pleiomorphic, severity is related to age and comorbidities such as diabetes and …

Characterization of SARS-CoV-2-specific humoral immunity and its potential applications and therapeutic prospects

J Zheng, Y Deng, Z Zhao, B Mao, M Lu, Y Lin… - Cellular & molecular …, 2022 - nature.com
Abstract Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), is an ongoing pandemic that poses a great threat to …

[HTML][HTML] Cell-type-specific immune dysregulation in severely ill COVID-19 patients

C Yao, SA Bora, T Parimon, T Zaman, OA Friedman… - Cell reports, 2021 - cell.com
Recent studies have demonstrated immunologic dysfunction in severely ill coronavirus
disease 2019 (COVID-19) patients. We use single-cell RNA sequencing (scRNA-seq) to …

Profound dysregulation of T cell homeostasis and function in patients with severe COVID‐19

S Adamo, S Chevrier, C Cervia, Y Zurbuchen… - Allergy, 2021 - Wiley Online Library
Abstract Background Coronavirus disease 2019 (COVID‐19) is caused by infection with
severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) and shows a broad clinical …

[HTML][HTML] COVID-19: Unanswered questions on immune response and pathogenesis

E Maggi, GW Canonica, L Moretta - Journal of Allergy and Clinical …, 2020 - Elsevier
The novel coronavirus disease 2019 has rapidly increased in pandemic scale since it first
appeared in Wuhan, China, in December 2019. In these troubled days the scientific …