Pulmonary fibrosis is characterized by lung inflammation and abnormal tissue repair,
resulting in the replacement of normal functional tissue with an abnormal accumulation of …

Pulmonary fibrosis is a highly heterogeneous and lethal pathological process with limited
therapeutic options. Although research on the pathogenesis of pulmonary fibrosis has …

Pulmonary fibrosis is a common response to various insults or injuries to the lung. Although
there are various initiating factors or causes, the terminal stages are characterized by …

Introduction Pulmonary fibrosis includes several lung disorders characterized by
progressive fibrosis, of which idiopathic pulmonary fibrosis (IPF) is a particularly severe form …

Idiopathic pulmonary fibrosis is a progressive lung disease that carries a poor prognosis and
for which there are no effective therapies. Although the excessive deposition of extracellular …

Idiopathic pulmonary fibrosis (IPF) is a progressive and terminal lung disease with no known
cure. IPF is a disease of aging, with median age of diagnosis over 65 years. Median survival …

Importance of the field: In fibrosing diseases, scar tissue begins to replace normal tissue,
causing tissue dysfunction. For instance, in lung fibrosis, foci of what resembles scar tissue …

Pulmonary fibrosis is a chronic lung disease characterized by excessive accumulation of
extracellular matrix (ECM) and remodeling of the lung architecture. Idiopathic pulmonary …

Idiopathic pulmonary fibrosis (IPF) is a chronic progressive disease of unknown cause
characterized by relentless scarring of the lung parenchyma leading to reduced quality of life …

The mechanisms of pulmonary fibrosis are complex, and several hypotheses have been put
forward to explain how fibrosis develops. It was long thought that inflammation was a key …