Novel thiazole-based thiazolidinones as potent anti-infective Agents: In silico PASS and toxicity prediction, Synthesis, Biological Evaluation and Molecular Modelling
C Tratrat - Combinatorial Chemistry & High Throughput …, 2020 - ingentaconnect.com
Aims and Objective: The infectious disease treatment remains a challenging concern owing
to the increasing number of pathogenic microorganisms associated with resistance to …
to the increasing number of pathogenic microorganisms associated with resistance to …
Thiazolidin-4-ones as potential antimicrobial agents: Experimental and in silico evaluation
Herein, we report computational and experimental evaluations of the antimicrobial activity of
twenty one 2, 3-diaryl-thiazolidin-4-ones. All synthesized compounds exhibited an …
twenty one 2, 3-diaryl-thiazolidin-4-ones. All synthesized compounds exhibited an …
5-benzyliden-2-(5-methylthiazol-2-ylimino) thiazolidin-4-ones as antimicrobial agents. design, synthesis, biological evaluation and molecular docking studies
In this study, we report the design, synthesis, computational and experimental evaluation of
the antimicrobial activity, as well as docking studies of new 5-methylthiazole based …
the antimicrobial activity, as well as docking studies of new 5-methylthiazole based …
Exploration of the antimicrobial effects of benzothiazolylthiazolidin-4-one and in silico mechanistic investigation
Background: Infectious diseases still affect large populations causing significant morbidity
and mortality. Bacterial and fungal infections for centuries were the main factors of death and …
and mortality. Bacterial and fungal infections for centuries were the main factors of death and …
Design, Synthesis, and Evaluation of Thiazolidinone Derivatives as Antimicrobial and Anti‐viral Agents
V Ravichandran, A Jain, KS Kumar… - Chemical biology & …, 2011 - Wiley Online Library
A series of 1, 3‐thiazolidin‐4‐one derivatives were prepared by the reaction of respective
aromatic amine, aromatic aldehyde, and thioglycolic acid in dry benzene/toluene. The newly …
aromatic amine, aromatic aldehyde, and thioglycolic acid in dry benzene/toluene. The newly …
Design, synthesis, antibacterial evaluations and in silico studies of novel thiosemicarbazides and 1, 3, 4-thiadiazoles
S Janowska, D Khylyuk, S Andrzejczuk, M Wujec - Molecules, 2022 - mdpi.com
The emergence of drug-resistant bacterial strains continues to be one of the major
challenges of medicine. For this reason, the importance of searching for novel structures of …
challenges of medicine. For this reason, the importance of searching for novel structures of …
Synthesis, Antimicrobial Evaluation, and In Silico Studies of 2-Substituted-Phenyl-3-(5-Aryl/Heteroaryl Substituted Thiazol-2-yl) Thiazolidin-4-One Derivatives
S Pawar, R Karan, S Hazarika, M Lal… - ASSAY and Drug …, 2024 - liebertpub.com
In a one-pot reaction involving 3-(2-aminothiazol-5-yl)-2 H-chromen-2-one/5-(naphthalen-1-
yl) thiazol-2-amines 5-6 with various substituted aldehydes and mercaptoacetic acid, we …
yl) thiazol-2-amines 5-6 with various substituted aldehydes and mercaptoacetic acid, we …
New benzothiazole-based thiazolidinones as potent antimicrobial agents. Design, synthesis and biological evaluation
Background: Thiazole and benzothiazole derivatives, as well as thiazolidinones are very
important scaffolds in medicinal chemistry. Literature has revealed that they possess a wide …
important scaffolds in medicinal chemistry. Literature has revealed that they possess a wide …
Design, Synthesis, Docking and Computational Pharmacokinetic Profiling of New Pyrazolinyl Thiazolinone Biheterocycles as Potent Antimicrobial Agents
Background: Development of potential antimicrobial agents is the main aim in the drug
discovery process to overcome the problem of drug resistance. Pyrazolines and …
discovery process to overcome the problem of drug resistance. Pyrazolines and …
5-Adamantan thiadiazole-based thiazolidinones as antimicrobial agents. Design, synthesis, molecular docking and evaluation
M Fesatidou, P Zagaliotis, C Camoutsis… - Bioorganic & Medicinal …, 2018 - Elsevier
In continuation of our efforts to develop new compounds with antimicrobial properties we
describe design, synthesis, molecular docking study and evaluation of antimicrobial activity …
describe design, synthesis, molecular docking study and evaluation of antimicrobial activity …