Methylglyoxal (MGO), a precursor of advanced glycation end products (AGEs), is regarded
as a pivotal mediator of vascular damage in patients with diabetes. We have previously …

Although methylglyoxal (MGO) has emerged as key mediator of diabetic microvascular
complications, the influence of MGO on the vascular transcriptome has not thoroughly been …

Endothelial dysfunction is a key risk factor in diabetes-related multiorgan damage.
Methylglyoxal (MGO), a highly reactive dicarbonyl generated primarily as a by-product of …

Endothelial dysfunction is an important factor in the development of vascular diseases such
as atherosclerosis, hypertension and diabetes. Methylglyoxal (MG) is a highly reactive …

Methylglyoxal (MGO) is a reactive dicarbonyl metabolite of glucose, and its plasma levels
are elevated in patients with diabetes. Studies have shown that MGO combines with the …

Methylglyoxal (MGO)-induced cellular apoptosis, oxidative stress, inflammation, and AGE
formation are specific events that induce vascular endothelial cell (EC) toxicity in endothelial …

Methylglyoxal (MGO), a highly reactive dicarbonyl compound, is a key precursor of the
formation of advanced glycation end products (AGEs). MGO and MGO-AGEs were …

Diabetes impairs physiological angiogenesis by molecular mechanisms that are not fully
understood. Methylglyoxal (MGO), a metabolite of glycolysis, is increased in patients with …

Methylglyoxal (MGO), a highly reactive dicarbonyl compound, is mainly formed as a
byproduct of glycolysis. Elevated MGO level is known to induce apoptosis of vascular …

Methylglyoxal (MGO) is a metabolite of glucose. Since serum MGO level is increased in
diabetic patients, MGO is implicated in diabetic complications related to vascular injury. We …