Agomelatine is a non-selective melatonin receptor agonist and an atypical antidepressant
with anti-inflammatory, neuroprotective, and cardioprotective effects. The renin-angiotensin …

Aims Melatonin is known to inhibit platelet aggregation induced by arachidonic acid (AA). In
the present study we investigated whether agomelatine (Ago), an antidepressant with …

Background/Aims: The development of atherosclerosis is accompanied by escalating
inflammation and lipid accumulation within blood vessel walls. ABCA1 plays a crucial role in …

Objectives The aim of this work was to explore possible effects of agmatine, an endogenous
inhibitor of inducible nitric oxide synthase (iNOS), against hypercholesterolemia-induced …

Atherosclerosis (AS) is an essential pathological changes of ischemic cardio-
cerebrovascular disease, and monocyte migration and adhesion to endothelial cells are the …

Lipid metabolism disorder and inflammatory response are considered to be the major
causes of atherosclerogenesis. Astragalin, the most important functional component of …

Background and aims Studies suggest that Gentiana lutea (GL), and its component
isovitexin, may exhibit anti-atherosclerotic properties. In this study we sought to investigate …

Inflammation plays an important role in the process of atherosclerosis (AS). Inhibition of
inflammation is an effective way to prevent AS. Imperatorin (IMP) is a kind of furan coumarin …

Endothelial dysfunction plays important roles in vascular dysfunction under diabetic
conditions. The generation of advanced glycation end products (AGEs), which can induce …

Apremilast is a phosphodiesterase 4 (PDE4) inhibitor used in the treatment of psoriasis and
several other inflammatory diseases. Interest has been expressed in seeking out therapies …