[HTML][HTML] Structures and mechanisms of nonsegmented, negative-strand RNA virus polymerases

M Ouizougun-Oubari, R Fearns - Annual Review of Virology, 2023 - annualreviews.org
The nonsegmented, negative-strand RNA viruses (nsNSVs), also known as the order
Mononegavirales, have a genome consisting of a single strand of negative-sense RNA …

Structure and function of negative-strand RNA virus polymerase complexes

JD Pyle, SPJ Whelan, LM Bloyet - The Enzymes, 2021 - Elsevier
Viruses with negative-strand RNA genomes (NSVs) include many highly pathogenic and
economically devastating disease-causing agents of humans, livestock, and plants …

[HTML][HTML] Towards a structural understanding of RNA synthesis by negative strand RNA viral polymerases

J Reguera, P Gerlach, S Cusack - Current opinion in structural biology, 2016 - Elsevier
Highlights•Crystal and cryo-EM structures of NSV polymerases influenza, La Crosse and
VSV.•Segmented and non-segmented NSV polymerases have a similar extended core …

The polymerase of negative-stranded RNA viruses

B Morin, PJ Kranzusch, AA Rahmeh… - Current opinion in …, 2013 - Elsevier
Highlights•Comparative structure and function analysis of RNA synthesis machinery of
negative-sense RNA viruses.•Unique biology of mRNA capping: cap snatching versus cap …

Structures of the Mononegavirales Polymerases

B Liang - Journal of Virology, 2020 - Am Soc Microbiol
Mononegavirales, known as nonsegmented negative-sense (NNS) RNA viruses, are a class
of pathogenic and sometimes deadly viruses that include rabies virus (RABV), human …

[HTML][HTML] Structural insights into RNA polymerases of negative-sense RNA viruses

AJW Te Velthuis, JM Grimes, E Fodor - Nature Reviews Microbiology, 2021 - nature.com
RNA viruses include many important human and animal pathogens, such as the influenza
viruses, respiratory syncytial virus, Ebola virus, measles virus and rabies virus. The …

Nonsegmented negative-sense RNA viruses—structural data bring new insights into nucleocapsid assembly

M Jamin, F Yabukarski - Advances in virus research, 2017 - Elsevier
Viruses with a nonsegmented negative-sense RNA genome (NNVs) include important
human pathogens as well as life-threatening zoonotic viruses. These viruses share a …

[HTML][HTML] Independent structural domains in paramyxovirus polymerase protein

M Dochow, SA Krumm, JE Crowe, ML Moore… - Journal of Biological …, 2012 - ASBMB
All enzymatic activities required for genomic replication and transcription of nonsegmented
negative strand RNA viruses (or Mononegavirales) are believed to be concentrated in the …

[HTML][HTML] Comparison of RNA synthesis initiation properties of non-segmented negative strand RNA virus polymerases

AM Shareef, B Ludeke, P Jordan, J Deval… - PLoS …, 2021 - journals.plos.org
It is generally thought that the promoters of non-segmented, negative strand RNA viruses
(nsNSVs) direct the polymerase to initiate RNA synthesis exclusively opposite the 3´ …

[HTML][HTML] The RNA synthesis machinery of negative-stranded RNA viruses

J Ortín, J Martín-Benito - Virology, 2015 - Elsevier
Abstract The group of Negative-Stranded RNA Viruses (NSVs) includes many human
pathogens, like the influenza, measles, mumps, respiratory syncytial or Ebola viruses, which …