AA El-Moamly, MA El-Sweify - Tropical Medicine and Health, 2023 - Springer
Background The world has made great strides towards beating malaria, although about half of the world population is still exposed to the risk of contracting malaria. Developing an …
MB Laurens - Human vaccines & immunotherapeutics, 2020 - Taylor & Francis
Malaria is an illness caused by Plasmodium parasites transmitted to humans by infected mosquitoes. Of the five species that infect humans, P. falciparum exacts the highest toll in …
AO Hassan, OV Oso, EI Obeagu… - … University journal of …, 2022 - madonnauniversity.edu.ng
Malaria is a life-threatening disease caused by the plasmodium genus, malaria can cause a range of symptoms and life–threatening complications so an early diagnosis is crucial. In …
RTS, S is the most advanced candidate vaccine against human malaria. During its remarkable journey from conception and design in the early 1980s to the multicenter Phase …
PD Crompton, SK Pierce… - The Journal of clinical …, 2010 - Am Soc Clin Investig
Malaria caused by Plasmodium falciparum remains a major public health threat, especially among children and pregnant women in Africa. An effective malaria vaccine would be a …
Abstract RTS, S/AS01 (Mosquirix®) is a vaccine against malaria caused by Plasmodium falciparum. In a phase 3 trial, RTS, S/AS01 showed vaccine efficacy against clinical malaria …
Malaria is a parasitic infection caused by bites from Plasmodium falciparum (P. falciparum)- infected mosquitoes with a present scale of symptoms ranging from moderate fever to …
In 2013 there were an estimated 584,000 deaths and 198 million clinical illnesses due to malaria, the majority in sub-Saharan Africa. Vaccines would be the ideal addition to the …
AJ Birkett, VS Moorthy, C Loucq, CE Chitnis… - Vaccine, 2013 - Elsevier
While recent progress has been made in reducing malaria mortality with other interventions, vaccines are still urgently needed to further reduce the incidence of clinical disease …