Translational Medicine in Acute Ischemic Stroke and Traumatic Brain Injury—NeuroAiD Trials, from Traditional Beliefs to Evidence-Based Therapy
N Venketasubramanian, TT Yeo, CLH Chen - Biomolecules, 2024 - mdpi.com
Acute ischemic stroke (AIS) and traumatic brain injury (TBI) are two severe neurological
events, both being major causes of death and prolonged impairment. Their incidence …
events, both being major causes of death and prolonged impairment. Their incidence …
Clinical Outcomes of MLC601 (NeuroAiDTM) in Traumatic Brain Injury: A Pilot Study
Background: MLC601 is a natural product formulation from Chinese medicine that is
extensively studied in ischemic stroke. Traumatic brain injury (TBI) shares …
extensively studied in ischemic stroke. Traumatic brain injury (TBI) shares …
The potential of MLC901 (NeuroAiD II™), a traditional Chinese medicine
S Huang, M Lin, X Pan, Q Tan, KL Tan - Neuroscience Research …, 2019 - neuroscirn.org
Stroke, also known as cerebral ischemia, is a common neurological disease. The
therapeutic potential of MLC901 (NeuroAiD II™) has been reported in clinical trials on …
therapeutic potential of MLC901 (NeuroAiD II™) has been reported in clinical trials on …
[HTML][HTML] Efficacy and safety of MLC601 (NeuroAiD®), a traditional Chinese medicine, in poststroke recovery: a systematic review
FJ Siddiqui, N Venketasubramanian… - Cerebrovascular …, 2013 - karger.com
Background: Subsequent to a pooled analysis of 2 trials, several more studies have been
published assessing the benefit of MLC601 in stroke patients. Hence, it is timely to conduct …
published assessing the benefit of MLC601 in stroke patients. Hence, it is timely to conduct …
Ischemic Stroke and Savings in Time to Achieve Functional Recovery: Experience from NeuroAiD
N Venketasubramanian, Y Pokharkar, JH Chai… - Journal of …, 2023 - mdpi.com
Despite recent progress with revascularisation interventions after acute ischemic stroke,
many patients remain disabled after stroke. Using data from a multi-centre, randomised …
many patients remain disabled after stroke. Using data from a multi-centre, randomised …
[HTML][HTML] Effect of combined treatment with MLC601 (NeuroAiDTM) and rehabilitation on post-stroke recovery: the CHIMES and CHIMES-E studies
NC Suwanwela, CLH Chen, CF Lee… - Cerebrovascular …, 2018 - karger.com
Background and Purpose: MLC601 has been shown in preclinical studies to enhance
neurorestorative mechanisms after stroke. The aim of this post hoc analysis was to assess …
neurorestorative mechanisms after stroke. The aim of this post hoc analysis was to assess …
The value of patient selection in demonstrating treatment effect in stroke recovery trials: lessons from the CHIMES study of MLC601 (NeuroAiD)
N Venketasubramanian, CF Lee… - Journal of Evidence …, 2015 - Wiley Online Library
Abstract Objective The CHIMES Study compared MLC601 to placebo in patients with
ischemic stroke of intermediate severity in the preceding 72 hours. We aimed to verify if …
ischemic stroke of intermediate severity in the preceding 72 hours. We aimed to verify if …
Safety profile of MLC601 (Neuroaid®) in acute ischemic stroke patients: a Singaporean substudy of the Chinese medicine neuroaid efficacy on stroke recovery study
SHY Young, Y Zhao, A Koh, R Singh… - Cerebrovascular …, 2010 - karger.com
Background: Previous clinical trials have shown that Neuroaid®(MLC601), a traditional
Chinese medicine, shows good tolerability and superiority over another traditional Chinese …
Chinese medicine, shows good tolerability and superiority over another traditional Chinese …
[HTML][HTML] Chinese medicine NeuroAiD efficacy stroke recovery-extension study (CHIMES-E study): an observational multicenter study to investigate the longer-term …
N Venketasubramanian, S Young, SS Tay… - Cerebrovascular …, 2013 - karger.com
Background: Stroke carries a poor long-term prognosis for death and disability. There are
few acute treatments that reduce death and disability after stroke. The ongoing international …
few acute treatments that reduce death and disability after stroke. The ongoing international …
[HTML][HTML] Neuroaid for improving recovery after ischemic stroke
C Zhang, W Tao, J Zhang, M Liu, J Li - The Cochrane Database of …, 2017 - ncbi.nlm.nih.gov
Neuroaid for improving recovery after ischemic stroke - PMC Back to Top Skip to main content
NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main Content Main …
NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main Content Main …