Covid-19—the search for effective therapy

LR Baden, EJ Rubin - New England Journal of Medicine, 2020 - Mass Medical Soc
Covid-19—The Search for Effective Therapy Lindsey Baden and Eric Rubin comment on the
findings of an urgent randomized clinical trial of a possible treatment for Covid-19 in Wuhan …

Treatment considerations for COVID-19: a critical review of the evidence (or lack thereof)

P Vijayvargiya, ZE Garrigos, NEC Almeida… - Mayo Clinic …, 2020 - Elsevier
The novel severe acute respiratory syndrome coronavirus 2 is causing a worldwide
pandemic that may lead to a highly morbid and potentially fatal coronavirus disease 2019 …

Current evidence for COVID-19 therapies: a systematic literature review

T Welte, LJ Ambrose, GC Sibbring… - European …, 2021 - Eur Respiratory Soc
Effective therapeutic interventions for the treatment and prevention of coronavirus disease
2019 (COVID-19) are urgently needed. A systematic review was conducted to identify …

Randomized clinical trials and COVID-19: managing expectations

H Bauchner, PB Fontanarosa - Jama, 2020 - jamanetwork.com
Despite the millions of cases and hundreds of thousands of deaths that have occurred in this
devastating coronavirus disease 2019 (COVID-19) pandemic, no peer-reviewed studies of …

COVID-19 treatment guidelines: do they really reflect best medical practices to manage the pandemic?

F Jirjees, AK Saad, Z Al Hano, T Hatahet… - Infectious Disease …, 2021 - mdpi.com
SARS-CoV-2 (COVID-19) has been changing the world since December 2019. A
comprehensive search into many COVID-19 treatment guidelines was conducted and …

[PDF][PDF] Clinical trials for the treatment of Coronavirus disease 2019 (COVID-19): A rapid response to urgent need

T Zhang, Y He, W Xu, A Ma, Y Yang… - Science China. Life …, 2020 - med.uminho.pt
Emerging coronavirus disease 2019, known as COVID-19, is caused by the newly identified
SARS-CoV-2 virus. Since the outbreak of COVID-19 in December 2019 in Wuhan (China) …

Systematic review of the registered clinical trials for coronavirus disease 2019 (COVID-19)

R Zhu, Y Gao, SH Robert, J Gao, S Yang… - Journal of translational …, 2020 - Springer
Background Since the outbreak of coronavirus disease 2019 (COVID-19), many researchers
in China have performed related clinical research. However, systematic reviews of the …

Ongoing clinical trials for the management of the COVID-19 pandemic

MP Lythgoe, P Middleton - Trends in pharmacological sciences, 2020 - cell.com
COVID-19 has rapidly developed into a worldwide pandemic with a significant health and
economic burden. There are currently no approved treatments or preventative therapeutic …

Treating COVID-19—off-label drug use, compassionate use, and randomized clinical trials during pandemics

AC Kalil - Jama, 2020 - jamanetwork.com
In the 2014 Ebola outbreak, close to 30 000 individuals developed Ebola viral disease
(EVD), and numerous therapies were tested against this virus, including chloroquine …

Pharmacologic treatments for coronavirus disease 2019 (COVID-19): a review

JM Sanders, ML Monogue, TZ Jodlowski, JB Cutrell - Jama, 2020 - jamanetwork.com
Importance The pandemic of coronavirus disease 2019 (COVID-19) caused by the novel
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) presents an …