Men consume the most nicotine and cannabis products but impacts on sperm epigenetics
are poorly characterized. Evidence suggests that preconception exposure to these drugs …

Little is known about the reproductive effects of paternal cannabis exposure. We evaluated
associations between cannabis or tetrahydrocannabinol (THC) exposure and altered DNA …

Abstract The United States is swiftly moving toward increased legalization of medical and
recreational cannabis. Currently considered the most commonly used illicit psychoactive …

Cannabis use in the United States is increasing, with highest consumption among men at
their peak reproductive years. We previously demonstrated widespread changes in sperm …

Background Cannabis legalization is expanding and men are the predominant users. We
have limited knowledge about how cannabis impacts sperm and whether the effects are …

Cannabis use alters sperm DNA methylation, but the potential reversibility of these changes
is unknown. Semen samples from cannabis users and non-user controls were collected at …

Developmental neurotoxicity of a wide variety of toxicants mediated via maternal exposure
during gestation is very well established. In contrast, the impacts of paternal toxicant …

Recent data from the Kollins lab ('Cannabinoid exposure and altered DNA methylation in rat
and human sperm'Epigenetics 2018; 13: 1208–1221) indicated epigenetic effects of …

Advanced paternal age (APA) has been shown to be a significant risk factor in the offspring
for neurodevelopmental psychiatric disorders, such as schizophrenia and autism spectrum …

Parental cannabis use has been associated with adverse neurodevelopmental outcomes in
offspring, but how such phenotypes are transmitted is largely unknown. Using reduced …