[HTML][HTML] Innate immunity, cytokine storm, and inflammatory cell death in COVID-19

R Karki, TD Kanneganti - Journal of Translational Medicine, 2022 - Springer
The innate immune system serves as the first line of defense against invading pathogens;
however, dysregulated innate immune responses can induce aberrant inflammation that is …

[HTML][HTML] Innate immune recognition against SARS-CoV-2

T Yamada, A Takaoka - Inflammation and Regeneration, 2023 - Springer
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is the causative virus of
pandemic acute respiratory disease called coronavirus disease 2019 (COVID-19). Most of …

[HTML][HTML] Innate immunity: the first line of defense against SARS-CoV-2

MS Diamond, TD Kanneganti - Nature immunology, 2022 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute
respiratory syndrome coronavirus (SARS-CoV)-2, continues to cause substantial morbidity …

COVID-19: immunology, immunopathogenesis and potential therapies

A Bhardwaj, L Sapra, C Saini, Z Azam… - International reviews …, 2022 - Taylor & Francis
Abstract The Coronavirus Disease-2019 (COVID-19) imposed public health emergency and
affected millions of people around the globe. As of January 2021, 100 million confirmed …

[HTML][HTML] Host cell-intrinsic innate immune recognition of SARS-CoV-2

EA Madden, MS Diamond - Current opinion in virology, 2022 - Elsevier
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) emerged at the end of
2019 and caused the pandemic of coronavirus disease 2019 (COVID-19). Basic and clinical …

[HTML][HTML] The innate immune system: fighting on the front lines or fanning the flames of COVID-19?

JL McKechnie, CA Blish - Cell host & microbe, 2020 - cell.com
The coronavirus disease 2019 (COVID-19) pandemic caused by SARS-CoV-2 has had
devastating global impacts and will continue to have dramatic effects on public health for …

[HTML][HTML] Innate immune signaling and proteolytic pathways in the resolution or exacerbation of SARS-CoV-2 in Covid-19: key therapeutic targets?

JM Sallenave, L Guillot - Frontiers in immunology, 2020 - frontiersin.org
COVID-19 is caused by the Severe Acute Respiratory Syndrome (SARS) coronavirus (Cov)-
2, an enveloped virus with a positive-polarity, single-stranded RNA genome. The initial …

Innate immunological pathways in COVID-19 pathogenesis

SR Paludan, TH Mogensen - Science immunology, 2022 - science.org
Coronavirus disease 2019 (COVID-19) is a disease characterized by a profound
dysregulation of the innate immune system. This knowledge has emerged from the large …

[HTML][HTML] SARS-CoV-2 and innate immunity: the good, the bad, and the “goldilocks”

BL Sievers, MTK Cheng, K Csiba, B Meng… - Cellular & Molecular …, 2024 - nature.com
An ancient conflict between hosts and pathogens has driven the innate and adaptive arms of
immunity. Knowledge about this interplay can not only help us identify biological …

[HTML][HTML] Innate immune response and inflammasome activation during SARS-CoV-2 infection

M Islamuddin, SA Mustfa, SNMN Ullah, U Omer, K Kato… - Inflammation, 2022 - Springer
The novel coronavirus SARS-CoV-2, responsible for the COVID-19 outbreak, has become a
pandemic threatening millions of lives worldwide. Recently, several vaccine candidates and …