The Self‐Controlled Case Series Design as a Viable Alternative to Studying Clinically Relevant Drug Interactions.
We congratulate Bykov I et al i.[1] on their use of the case-crossover design to screen
electronic healthcare data for clinically important drug-drug interactions (DDIs). By nature of …
electronic healthcare data for clinically important drug-drug interactions (DDIs). By nature of …
Response to “The Self-Controlled Case Series Design as a Viable Alternative to Studying Clinically-Relevant Drug Interactions”
We thank Zhou and colleagues for their thoughtful comments on our paper “A Case-
Crossover-Based Screening Approach to Identifying Clinically Relevant Drug-Drug …
Crossover-Based Screening Approach to Identifying Clinically Relevant Drug-Drug …
Drug‐drug interaction surveillance study: comparing self‐controlled designs in five empirical examples in real‐world data
Self‐controlled designs, specifically the case‐crossover (CCO) and the self‐controlled case
series (SCCS), are increasingly utilized to generate real‐world evidence (RWE) on drug …
series (SCCS), are increasingly utilized to generate real‐world evidence (RWE) on drug …
Comparison of self-controlled designs for evaluating outcomes of drug–drug interactions: simulation study
Background: Self-controlled designs, both case–crossover and self-controlled case series,
are well suited for evaluating outcomes of drug–drug interactions in electronic healthcare …
are well suited for evaluating outcomes of drug–drug interactions in electronic healthcare …
The case–crossover design for drug–drug interactions: considerations for implementation
Background: The case–crossover design may be useful for evaluating the clinical impact of
drug–drug interactions in electronic healthcare data; however, experience with the design in …
drug–drug interactions in electronic healthcare data; however, experience with the design in …
[PDF][PDF] Commentary: Use of point-in-time or window approach in the case-crossover design, implications for pharmacoepidemiologic research using registries.
J Hallas, M Maclure - 2024 - authorea.com
The case-crossover design and similar outcome-anchored case-only designs compare
exposure frequency in a window immediately or shortly before an outcome ('focal window') …
exposure frequency in a window immediately or shortly before an outcome ('focal window') …
Examining the Use of Case-Crossover Design With Non-Transient Medication Exposures
HC Huang - 2023 - search.proquest.com
Observational studies are an important study design in pharmacoepidemiology research
especially when examining the safety of medications. Compared to randomized controlled …
especially when examining the safety of medications. Compared to randomized controlled …
Methodological Considerations on the Use of Cohort Designs in Drug-Drug Interaction Studies in Pharmacoepidemiology
Abstract Purpose of Review The evidence regarding the clinical effects of drug-drug
interactions (DDIs) is scarce and limited. Pharmacoepidemiologic studies could help fill in …
interactions (DDIs) is scarce and limited. Pharmacoepidemiologic studies could help fill in …
Spotlight commentary: The value of spontaneous reporting systems to detect (the lack of) clinically relevant drug–drug interactions in clinical practice.
E Raschi, E Poluzzi, F De Ponti - British Journal of Clinical …, 2023 - search.ebscohost.com
Drug-drug interaction of the sodium glucose co-transporter 2 inhibitors with statins and
myopathy: a disproportionality analysis using adverse events reporting data. Keywords …
myopathy: a disproportionality analysis using adverse events reporting data. Keywords …
Methods for Studying the Health Effects of Drug–Drug Interactions
A drug–drug interaction (DDI) occurs when one or more drugs affect the pharmacokinetics
and/or pharmacodynamics of one or more other drugs. Pharmacoepidemiology studies are …
and/or pharmacodynamics of one or more other drugs. Pharmacoepidemiology studies are …