The circFASN/miR-33a pathway participates in tacrolimus-induced dysregulation of hepatic triglyceride homeostasis

C Zhang, K Chen, R Wei, G Fan, X Cai, L Xu… - Signal transduction and …, 2020 - nature.com
Dyslipidemia exhibits a high incidence after liver transplantation, in which tacrolimus, a
widely used immunosuppressant, plays a fundamental role. MicroRNAs and related …

CircRNA-PI4KB induces hepatic lipid deposition in non-alcoholic fatty liver disease by transporting miRNA-122 to extra-hepatocytes

CH Liu, W Jiang, Q Zeng, D Wu, H Li, L Zhou… - International Journal of …, 2023 - mdpi.com
Ectopic fat deposition in the liver, known as non-alcoholic fatty liver disease (NAFLD), affects
up to 30% of the worldwide population. miRNA-122, the most abundant liver-specific …

[HTML][HTML] circRNA_0046366 inhibits hepatocellular steatosis by normalization of PPAR signaling

XY Guo, F Sun, JN Chen, YQ Wang… - World Journal of …, 2018 - ncbi.nlm.nih.gov
METHODS The effect of circRNA on miR-34a was recognized by the miRNA response
element (MRE), and validated by the dual-luciferase reporter assay. Its association with …

circRNA_0046367 prevents hepatoxicity of lipid peroxidation: an inhibitory role against hepatic steatosis

XY Guo, JN Chen, F Sun, YQ Wang… - … medicine and cellular …, 2017 - Wiley Online Library
Hepatic steatosis reflects the miRNA‐related pathological disorder with triglyceride
accumulation and lipid peroxidation, which leads to nonalcoholic steatohepatitis, liver …

circRNA hsa_circ_104566 sponged miR-338-3p to promote hepatocellular carcinoma progression

G Liu, W Guo, M Rao, J Qin, F Hu, K Li - Cell Transplantation, 2020 - journals.sagepub.com
Circular RNAs (circRNAs) could sponge micro-RNAs (miRNAs) to regulate tumor
progression of hepatocellular carcinoma (HCC). Hsa_circ_104566 contributes to papillary …

CircRNF111 protects against insulin resistance and lipid deposition via regulating miR-143-3p/IGF2R axis in metabolic syndrome

X Lin, Y Du, W Lu, W Gui, S Sun, Y Zhu… - Frontiers in Cell and …, 2021 - frontiersin.org
Abnormal expression of circRNAs (circular RNAs), a subclass of non-coding RNAs, has
been documented in numerous human diseases. Herein, we explored whether circRNAs act …

CircScd1 promotes fatty liver disease via the janus kinase 2/signal transducer and activator of transcription 5 pathway

P Li, K Shan, Y Liu, Y Zhang, L Xu, L Xu - Digestive diseases and sciences, 2019 - Springer
Background Nonalcoholic fatty liver disease (NAFLD) is one of the most common liver
diseases in affluent countries. Recent studies have reported that circular RNAs (circRNAs) …

circELMOD3 increases and stabilizes TRIM13 by sponging miR-6864-5p and direct binding to inhibit HCC progression

M Lai, M Liu, D Li, R Zhang, L Wang, X Li, S Chen… - Iscience, 2023 - cell.com
Many circular RNAs (circRNAs) have been identified to be associated with hepatocellular
carcinoma (HCC) progression. We aim to explore the diagnostic potential, functions, and …

circFOXM1 contributes to sorafenib resistance of hepatocellular carcinoma cells by regulating MECP2 via miR-1324

H Weng, L Zeng, L Cao, T Chen, Y Li, Y Xu… - … Therapy-Nucleic Acids, 2021 - cell.com
As one of the most common malignant tumors, hepatocellular carcinoma (HCC) is a leading
cause of cancer-related deaths around the world. Emerging studies have indicated that …

Comprehensive evaluation of circRNAs in cirrhotic cardiomyopathy before and after liver transplantation

Y Zhang, Z Wang, L Zhao, M Wen, J Li, Q Lv… - International …, 2023 - Elsevier
Cirrhotic cardiomyopathy (CCM) is a common complication of liver cirrhosis. Many patients
with cirrhotic livers do not die from liver failure but from abnormal hemodynamics secondary …